Recent Advances of Fluid Manipulation Technologies in Microfluidic Paper-Based Analytical Devices (μPADs) toward Multi-Step Assays

Micromachines
Taehoon H KimMinseok S Kim

Abstract

Microfluidic paper-based analytical devices (μPADs) have been suggested as alternatives for developing countries with suboptimal medical conditions because of their low diagnostic cost, high portability, and disposable characteristics. Recently, paper-based diagnostic devices enabling multi-step assays have been drawing attention, as they allow complicated tests, such as enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR), which were previously only conducted in the laboratory, to be performed on-site. In addition, user convenience and price of paper-based diagnostic devices are other competitive points over other point-of-care testing (POCT) devices, which are more critical in developing countries. Fluid manipulation technologies in paper play a key role in realizing multi-step assays via μPADs, and the expansion of biochemical applications will provide developing countries with more medical benefits. Therefore, we herein aimed to investigate recent fluid manipulation technologies utilized in paper-based devices and to introduce various approaches adopting several principles to control fluids on papers. Fluid manipulation technologies are classified into passive and active methods. While passive valve...Continue Reading

References

Sep 23, 2003·Clinical Chemistry·Natalie KhuseyinovaWolfgang Koenig
Apr 4, 2006·Analytical Chemistry·Byoungsok JungJuan G Santiago
Jan 11, 2007·Angewandte Chemie·Andres W MartinezGeorge M Whitesides
Nov 22, 2008·Lab on a Chip·Andres W MartinezGeorge M Whitesides
Dec 10, 2008·Proceedings of the National Academy of Sciences of the United States of America·Andres W MartinezGeorge M Whitesides
Jun 12, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·David M WhileyTheo P Sloots
Jun 25, 2009·Analytical Chemistry·Xu LiWei Shen
Oct 23, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Sergio MendezGabriel P López
Mar 20, 2010·Lab on a Chip·Elain FuPaul Yager
Jan 28, 2009·ACS Applied Materials & Interfaces·Erin M FentonScott S Sibbett
Apr 24, 2010·Analytical Chemistry·Hyeran Noh, Scott T Phillips
Jul 31, 2010·Lab on a Chip·Andres W MartinezGeorge M Whitesides
Aug 4, 2010·Analytica Chimica Acta·Wijitar DungchaiCharles S Henry
Aug 14, 2010·Sensors and Actuators. B, Chemical·Elain FuPaul Yager
Sep 3, 2010·Analytical Chemistry·Hyeran Noh, Scott T Phillips
Nov 10, 2010·Analytical Chemistry·Wei W Yu, Ian M White
Nov 26, 2010·Analytical Chemistry·Juuso OlkkonenTomi Erho
Jan 26, 2011·Lab on a Chip·Girish ChitnisBabak Ziaie
Oct 19, 2011·Journal of the American Chemical Society·Hong Liu, Richard M Crooks
Dec 6, 2011·Microfluidics and Nanofluidics·Elain FuPaul Yager
Jan 11, 2012·Analytical Chemistry·Kevin M SchillingAndres W Martinez
Jul 28, 2012·Environmental Science & Technology·Alexander D BeatonHywel Morgan
Oct 20, 2012·Lab on a Chip·Sana Jahanshahi-AnbuhiCarlos D M Filipe
Apr 17, 2013·Analytical Chemistry·Hong LiuRichard M Crooks
Jul 6, 2013·The Analyst·Charmaine K W KooSam R Nugen
Aug 13, 2013·Analytical Chemistry·Christophe RenaultRichard M Crooks
Nov 16, 2013·Analytical Chemistry·Jared HoughtalingElain Fu
Nov 20, 2013·Analytical Chemistry·Bhushan J ToleyElain Fu
Mar 19, 2014·Journal of the American Chemical Society·Christophe RenaultRichard M Crooks

❮ Previous
Next ❯

Citations

Jul 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Siraprapa BoobphahomKwanwoo Shin
Feb 6, 2021·Biosensors & Bioelectronics·Sidharth ModhaHideaki Tsutsui
Jun 15, 2021·Chemical Reviews·Eka NovianaCharles S Henry

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay
chemical treatment
ELISA
chips
enzymatic assay

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annual Review of Analytical Chemistry
Xiao Jiang, Z Hugh Fan
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Wei Yin LimSook Mei Khor
Annual Review of Analytical Chemistry
Tugba OzerCharles S Henry
© 2021 Meta ULC. All rights reserved