Recent antiviral strategies against human coronavirus-related respiratory illnesses

Current Opinion in Pulmonary Medicine
Anna Golda, Krzysztof Pyrc

Abstract

The main purpose of this review is to summarize the current research (2006-2007) concerning the development of novel anticoronaviral strategies and compounds. Recent research led to the identification of several novel agents inhibiting coronaviral replication. The most promising compounds include carbohydrate-binding agents, neutralizing antibodies and drugs targeting a coronaviral envelope protein. Although initial outbreaks of coronavirus that causes severe acute respiratory syndrome (SARS-CoV) were controlled by public health measures, the development of vaccines and antiviral agents for SARS-CoV is essential for improving control and treatment of future outbreaks. Four years after the SARS-CoV epidemic, several compounds with an anticoronaviral activity have been identified.

References

May 1, 1992·Cell·L H PintoR A Lamb
Jun 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·R VlasakP Palese
Jan 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·D Hamre, J J Procknow
Apr 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·K McIntoshR M Chanock
Dec 1, 1983·The Journal of General Virology·D Cavanagh
Jun 1, 1997·Journal of the American Geriatrics Society·A R FalseyJ E Kolassa
Aug 26, 1999·Trends in Genetics : TIG·A Fire
Jun 10, 2000·Science·J Marx
Oct 19, 2000·The Journal of Cell Biology·R W Doms, J P Moore
Jun 8, 2001·Annual Review of Biochemistry·D M Eckert, P S Kim
Apr 12, 2003·The New England Journal of Medicine·Christian DrostenHans Wilhelm Doerr
Apr 12, 2003·The New England Journal of Medicine·Thomas G KsiazekUNKNOWN SARS Working Group
Apr 25, 2003·Lancet·J S M PeirisUNKNOWN SARS study group
Jun 5, 1965·British Medical Journal·D A TYRRELL, M L BYNOE
Mar 23, 2004·Nature Medicine·Lia van der HoekBen Berkhout
May 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Berend Jan BoschPeter J M Rottier
Nov 6, 2004·Virology·Lauren WilsonGary Ewart
Nov 19, 2004·Virology Journal·Krzysztof PyrcLia van der Hoek
Dec 28, 2004·Nature Medicine·Vira BitkoSailen Barik
Mar 15, 2005·Scandinavian Journal of Infectious Diseases·Helena DahlOrjan Strannegård
May 18, 2005·Proceedings of the National Academy of Sciences of the United States of America·Heike HofmannStefan Pöhlmann
Jul 30, 2005·Scandinavian Journal of Infectious Diseases·Danai SofianouAthanassios Tsakris
Aug 18, 2005·PLoS Medicine·Lia van der HoekKlaus Uberla
Sep 24, 2005·Gene Therapy·J N Leonard, D V Schaffer
Nov 4, 2005·The Journal of Infectious Diseases·Patrick C Y WooKwok-Yung Yuen
Dec 7, 2005·Biochemical and Biophysical Research Communications·Ping WeiLuhua Lai
Dec 13, 2005·Microbiology and Molecular Biology Reviews : MMBR·Susan R Weiss, Sonia Navas-Martin
Feb 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Astrid VabretFrançois Freymuth
Apr 14, 2006·Current Pharmaceutical Design·D N Frick, A M I Lam
May 4, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yuxian HeShibo Jiang
May 16, 2006·Journal of Structural Biology·Brian TripetRobert S Hodges
May 26, 2006·Antimicrobial Agents and Chemotherapy·Krzysztof PyrcLia van der Hoek
Jun 9, 2006·Journal of Medicinal Chemistry·Lu ZhouLuhua Lai
Jun 9, 2006·Journal of Medicinal Chemistry·Keng-Chang TsaiSu-Ying Wu
Jul 18, 2006·Nucleic Acids Research·Yuki NaitoKaoru Saigo

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Citations

Mar 23, 2011·The Journal of Infectious Diseases·Mike BrayDaniel J Mollura
Jul 19, 2011·Future Virology·Dale L Barnard, Yohichi Kumaki
Feb 23, 2010·Infectious Disease Clinics of North America·Dennis J CleriJohn R Vernaleo
Sep 15, 2009·Virology·Melissa M CoughlinBellur S Prabhakar
Feb 18, 2011·The Journal of General Virology·Anna GoldaKrzysztof Pyrc
Jun 4, 2021·Frontiers in Pharmacology·Alshaimaa M HamodaSameh S M Soliman

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