Recent Asian origin of chytrid fungi causing global amphibian declines.

Science
S J O'HanlonMatthew C Fisher

Abstract

Globalized infectious diseases are causing species declines worldwide, but their source often remains elusive. We used whole-genome sequencing to solve the spatiotemporal origins of the most devastating panzootic to date, caused by the fungus Batrachochytrium dendrobatidis, a proximate driver of global amphibian declines. We traced the source of B. dendrobatidis to the Korean peninsula, where one lineage, BdASIA-1, exhibits the genetic hallmarks of an ancestral population that seeded the panzootic. We date the emergence of this pathogen to the early 20th century, coinciding with the global expansion of commercial trade in amphibians, and we show that intercontinental transmission is ongoing. Our findings point to East Asia as a geographic hotspot for B. dendrobatidis biodiversity and the original source of these lineages that now parasitize amphibians worldwide.

References

Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·L BergerH Parkes
Jan 27, 1999·Bioinformatics·D Posada, K A Crandall
Jun 3, 2000·Genetics·J K PritchardP Donnelly
Sep 4, 2003·Genome Research·Li LiDavid S Roos
Jan 25, 2005·Emerging Infectious Diseases·Ché WeldonRick Spears
Aug 23, 2006·Ecology·Lara J RachowiczCheryl J Briggs
Sep 8, 2006·Diseases of Aquatic Organisms·Kerry M KrigerJean-Marc Hero
Sep 25, 2008·Current Biology : CB·Susan F WalkerMatthew C Fisher
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Jan 27, 2011·Nucleic Acids Research·Matus ValachJozef Nosek
Feb 22, 2011·Bioinformatics·Diego DarribaDavid Posada
May 6, 2011·Proceedings of the National Academy of Sciences of the United States of America·Tina L ChengVance T Vredenburg
Jun 10, 2011·Bioinformatics·Petr DanecekUNKNOWN 1000 Genomes Project Analysis Group
Nov 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Rhys A FarrerMatthew C Fisher
Nov 25, 2011·Genome Biology and Evolution·Ehsan KayalDennis V Lavrov
Feb 1, 2012·PLoS Genetics·Daniel John LawsonDaniel Falush
Mar 1, 2012·Molecular Biology and Evolution·Alexei J DrummondAndrew Rambaut
Apr 14, 2012·Nature·Matthew C FisherSarah J Gurr
Jun 8, 2012·Evolution; International Journal of Organic Evolution·Emilien LuquetSandrine Plénet
May 8, 2013·Proceedings of the National Academy of Sciences of the United States of America·Erica Bree RosenblumJason E Stajich
Sep 11, 2013·Ecology·Benjamin J DoddingtonMatthew C Fisher
Oct 8, 2013·American Journal of Human Genetics·Olivier DelaneauJonathan Marchini
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jan 24, 2014·Bioinformatics·Philip JonesSarah Hunter
May 30, 2014·Nature·Jonathan E Kolby
Dec 3, 2014·Current Biology : CB·Stephen J PriceJaime Bosch
Jan 16, 2015·Diseases of Aquatic Organisms·Sanjay MolurNeelesh Dahanukar
Feb 24, 2015·Bioinformatics·Adrian TanHyun Min Kang

❮ Previous
Next ❯

Citations

Jun 5, 2019·Proceedings. Biological Sciences·Minjie Fu, Bruce Waldman
Sep 25, 2019·Proceedings of the National Academy of Sciences of the United States of America·Allison Q ByrneErica Bree Rosenblum
Oct 9, 2019·Proceedings of the National Academy of Sciences of the United States of America·Amy McDermott
Nov 9, 2019·Conservation Biology : the Journal of the Society for Conservation Biology·Rogier E HintzenJames Rosindell
Nov 11, 2019·Applied and Environmental Microbiology·Blanca B LandaRodrigo P P Almeida
Dec 25, 2019·The Journal of Animal Ecology·Kirsten M McMillanTrenton W J Garner
Jan 23, 2020·Genes·Himeshi SamarasingheTimothy Y James
Feb 14, 2020·PLoS Pathogens·Aurelie ChambouvetThomas A Richards
Apr 12, 2020·Transboundary and Emerging Diseases·Patricia A BurrowesIgnacio De la Riva
Sep 20, 2019·PloS One·Vance T VredenburgCheryl J Briggs
May 12, 2020·PLoS Genetics·Polina Yu NovikovaStephen C Donnellan
Feb 27, 2020·Nature Reviews. Microbiology·Matthew C Fisher, Trenton W J Garner
Apr 29, 2020·Ecological Applications : a Publication of the Ecological Society of America·Sara C BellLee F Skerratt
Apr 21, 2020·Molecular Ecology·Cait A McDonaldKelly R Zamudio
Apr 10, 2019·Proceedings. Biological Sciences·Thomas S JenkinsonTimothy Y James
Mar 30, 2019·Science·Dan A Greenberg, Wendy J Palen
Jul 4, 2020·Diseases of Aquatic Organisms·Kristyn A RobinsonLillian Fritz-Laylin
Apr 2, 2020·BMC Genetics·Maria Cortázar-ChinarroJacob Höglund
Sep 19, 2019·Scientific Reports·Luisa P RibeiroLuís Felipe Toledo
May 18, 2020·Environmental Science and Pollution Research International·Richard A Brain, Julie C Anderson
Aug 25, 2020·Biodiversity and Conservation·Dirk S SchmellerGerry Killeen
May 12, 2018·Science·Karen Lips
Nov 27, 2018·Frontiers in Immunology·Laura F GroganHamish I McCallum
Sep 27, 2018·Frontiers in Genetics·Pria N GhoshKieran A Bates
Feb 11, 2020·Frontiers in Microbiology·Xavier A HarrisonRachael E Antwis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.