Recent bacterial and viral infection is a risk factor for cerebrovascular ischemia: clinical and biochemical studies

Neurology
A J GrauW Hacke

Abstract

We performed a case-control study to investigate the role of recent infection as stroke risk factor and to identify pathogenetic pathways linking infection and stroke. We examined 166 consecutive patients with acute cerebrovascular ischemia and 166 patients hospitalized for nonvascular and noninflammatory neurologic diseases. Control subjects were individually matched to patients for sex, age, and season of admission. We assessed special biochemical parameters in subgroups of stroke patients with and without recent infection (n = 21) who were similar with respect to demographic and clinical parameters. Infection within the preceding week was a risk factor for cerebrovascular ischemia in univariate (odds ratio [OR] 3.1; 95% confidence interval (CI), 1.57 to 6.1) and age-adjusted multiple logistic regression analysis (OR 2.9; 95% CI, 1.31 to 6.4). The OR of recent infection and age were inversely related. Both bacterial and viral infection contributed to increased risk. Infection elevated the risk for cardioembolism and tended to increase the risk for arterioarterial embolism. Stroke patients with and without preceding infection were not different with respect to factor VII and factor VIII activity, fibrin monomer, fibrin D-dimer...Continue Reading

References

Aug 11, 1991·Stroke; a Journal of Cerebral Circulation·S F AmerisoM Fisher
Jan 4, 1990·The New England Journal of Medicine·J M KaldorS Karjalainen
Jan 2, 1988·British Medical Journal·T Smith
May 1, 1988·Stroke; a Journal of Cerebral Circulation·A D'AngeloP M Mannucci
Oct 1, 1986·Clinical Immunology and Immunopathology·O VaaralaK Aho
Jan 1, 1995·Stroke; a Journal of Cerebral Circulation·E ShaharH Blackburn
Jan 1, 1993·Advances in Immunology·S AkiraT Kishimoto
Jan 1, 1996·Stroke; a Journal of Cerebral Circulation·B E PollockD Kondziolka

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Citations

Oct 27, 2004·Journal of Neurology·T UmapathiSze Peng Brenda Ang
Dec 4, 2003·Mund-, Kiefer- und Gesichtschirurgie : MKG·A BüchterJ Kleinheinz
May 9, 2003·The Annals of Thoracic Surgery·Alexander A AlbertJürgen Ennker
Dec 3, 1999·Journal of the Neurological Sciences·A J GrauW Hacke
Mar 27, 2003·Pediatric Neurology·Battista GuidiMarinella Portolani
Jul 24, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Donald M Peebles, John S Wyatt
Nov 10, 2010·Nature Reviews. Neurology·Armin J GrauFrederick Palm
Dec 12, 2001·European Journal of Clinical Investigation·A J GrauC Grond-Ginsbach
Feb 24, 2001·Journal of the American Geriatrics Society·J D Shenkin, B J Baum
Sep 9, 1999·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C FerrareseM G De Simoni
Jun 18, 1999·Archives of Disease in Childhood·F J Kirkham
Oct 12, 2010·Stroke; a Journal of Cerebral Circulation·Mitchell S V Elkind
May 7, 2011·Stroke; a Journal of Cerebral Circulation·Mitchell S V ElkindW T Longstreth
Dec 7, 2013·BMC Neurology·Mahmoud Reza AzarpazhoohAmir Azarpazhooh
Aug 3, 2011·Annals of Indian Academy of Neurology·N K RaiM V Padma
Jan 5, 2014·Current Neurology and Neuroscience Reports·Adam L Numis, Christine K Fox
Nov 3, 2010·Journal of Pediatric Neurosciences·Julius Alexander Ogeng'oSimeon R Sinkeet
Jan 5, 2010·Wiener klinische Wochenschrift·Marko KutlesaNina Barisić
Jan 12, 2007·Current Opinion in Neurology·Mitchell S V Elkind
May 15, 2007·Current Opinion in Neurology·Keith W MuirElizabeth Warburton
Nov 6, 2007·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Rolf P KreutzPaul A Gurbel
Sep 23, 2006·Expert Review of Vaccines·Christoph Lichy, Armin J Grau
Apr 5, 2014·International Journal of Environmental Research and Public Health·Hui-Chen LinChun-Yuh Yang
Oct 3, 2006·Expert Review of Neurotherapeutics·Radoslaw Kazmierski
Jan 8, 2013·Pediatric Neurology·Aleksandra Mineyko, Adam Kirton
Sep 16, 2008·Neuroscience·B W McCollN J Rothwell
Mar 15, 2008·Lancet Neurology·Hedley C A Emsley, Stephen J Hopkins
Jun 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Hiroyuki TsukuiRobert L Kormos
Nov 14, 2006·Vaccine·Chong-Shan WangPesus Chou
Oct 2, 2015·Neurology·Heather J FullertonUNKNOWN VIPS Investigators
Apr 17, 2004·Journal of Clinical Periodontology·Christof E DörferArmin J Grau
Apr 5, 2013·Acta Neurologica Scandinavica·L-N ChienH-Y Chiou
Oct 20, 2010·Annals of the New York Academy of Sciences·Mitchell S V Elkind
Jan 3, 2013·Annals of Neurology·Nancy K HillsHeather J Fullerton
Jan 3, 2013·Annals of Neurology·Gabrielle deVeber
Jul 13, 2004·Pediatric Neurology·Michael L Bell, Jeffrey R Buchhalter
Nov 19, 2009·Biochemical and Biophysical Research Communications·Yeqing TongZuxun Lu
Aug 21, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Callum M DupreThomas Kwiatkowski
Jul 12, 2014·Chinese Journal of Integrative Medicine·Thanasekaran JayakumarJoen-rong Sheu
Aug 2, 2005·Arquivos de neuro-psiquiatria·Cynthia Resende CamposDemétrius Kasak P Abrahão

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