PMID: 8287391Nov 1, 1993Paper

Recent cardiovascular drugs from Chinese medicinal plants

Cardiovascular Research
M C Sutter, Y X Wang

Abstract

This paper describes the pharmacology of some recent cardiovascular drugs derived from plants used in Chinese traditional medicine. The groups of compounds discussed are benzylisoquinolines (several), tetrahydropyrazine (also called ligustrazine), rhynchophylline and hirsutine, ginkgolides and other PAF inhibitors, coumarins, and ginsenosides, plus a miscellaneous group; approximately 30 substances in all. The plant sources and the pharmacology are indicated for the drugs in each group. By far the most studied compounds are the benzylisoquinolines, especially tetrandrine. The types of pharmacological activity recently described for cardiovascular drugs from plants include calcium antagonism, adrenoceptor antagonism, antagonism of platelet activating factor (PAF), and the ability to act as antioxidants. Hundreds of chemicals have been isolated and identified as constituents of thousands of plants but the basic and clinical pharmacology is known for only a handful of these drugs. Much more research is needed, especially with regard to the pharmacology, both basic and clinical, of the pure chemicals derived from plants.

Citations

Nov 5, 1999·Journal of Biomedical Science·M J SuT S Wu
Feb 14, 2009·Disease-a-month : DM·William H FrishmanChristine Carosella
Mar 12, 2003·Addictive Behaviors·Kyle KampmanCharles O'Brien
Feb 18, 2009·Journal of Gastroenterology and Hepatology·Josette S Y ChorJoseph J Y Sung
May 12, 2000·Journal of Clinical Pharmacology·J T Cheng
May 11, 2011·Pharmaceutical Biology·Fengrong JiangChang Liu
Aug 20, 2011·Drug Development and Industrial Pharmacy·Xiao YanyuNiu Jiangxiu
May 22, 2010·Journal of Molecular Graphics & Modelling·Xi ZhouXin Chen
Mar 30, 2010·Journal of Ethnopharmacology·Li-fang LuoDong-sheng Ouyang
Dec 15, 2015·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Subha RastogiA K S Rawat
May 15, 2004·The Journal of Pharmacy and Pharmacology·Wang-Chuan ChenJuei-Tang Cheng
Jul 16, 2005·Current Problems in Cardiology·William H FrishmanRavinder Mamtani
Jun 21, 2015·Journal of Ethnopharmacology·Qian ZhangWei Qu
Feb 26, 2004·The Journal of Pharmacy and Pharmacology·X-C YuT M Wong
May 24, 2016·International Journal of Antimicrobial Agents·Lele Song, Xueqiong Wu
Jan 6, 2017·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Nai-Fei HuYun-Fang Gao
Apr 12, 2013·Cerebrovascular Diseases·Marie-Germaine Bousser
Feb 10, 2004·Cardiology in Review·Mina K Chung
Aug 23, 2018·Phytotherapy Research : PTR·Zahra GholamnezhadMohammad Hossein Boskabady
Mar 1, 2018·Pharmaceutical Biology·Emily Guzman, Jeanmaire Molina
Nov 2, 2018·Chemical Biology & Drug Design·Angamba Meetei PotshangbamVaibhav Vindal
Dec 20, 2007·Plastic and Reconstructive Surgery·Benjamin W BeckertCharles L Puckett
Sep 22, 2005·Clinical and Experimental Pharmacology & Physiology·Chiu-Yin KwanShujiro Seo
May 1, 1996·Journal of Cardiovascular Pharmacology·L ChenS S Lee
Jul 18, 2002·Holistic Nursing Practice·J A Sutherland
Oct 20, 2011·The Journal of Toxicological Sciences·Young-Seob LeeDong-Yeul Kwon
Apr 1, 2009·Journal of Natural Products·Chun-Hsiao ChouYuk-Man Leung
Sep 1, 1994·Japanese Journal of Pharmacology·T KatoM Sakanashi
Jun 1, 1997·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·H VuorelaS Alaranta

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