Recent development trends for chiral stationary phases based on chitosan derivatives, cyclofructan derivatives and chiral porous materials in high performance liquid chromatography

Journal of Separation Science
Sheng-Ming Xie, Li-Ming Yuan

Abstract

The separation of enantiomers by chromatographic methods, such as gas chromatography, high-performance liquid chromatography and capillary electrochromatography, has become an increasingly significant challenge over the past few decades due to the demand of pharmaceutical, agrochemical, and food analysis. Among these chromatographic resolution methods, high-performance liquid chromatography based on chiral stationary phases has become the most popular and effective method used for the analytical and preparative separation of optically active compounds. This review mainly focuses on the recent development trends for novel chiral stationary phases based on chitosan derivatives, cyclofructan derivatives, and chiral porous materials that include metal-organic frameworks and covalent organic frameworks in high-performance liquid chromatography. The enantioseparation performance and chiral recognition mechanisms of these newly developed chiral selectors toward enantiomers are discussed in detail.

References

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Citations

Mar 3, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joana TeixeiraCarla Fernandes
Nov 2, 2019·Journal of Separation Science·Datong WuYong Kong
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuan ZhaoBaoguo Sun
Jul 3, 2021·Journal of Separation Science·Benjamin D SlaterBradley P Ladewig
Aug 4, 2021·ACS Applied Materials & Interfaces·Zhen-Zhang WengLan-Sun Zheng
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Róbert BerkeczIstván Ilisz
Mar 17, 2020·ACS Applied Materials & Interfaces·Yunyan YuLiming Yuan
Nov 23, 2021·Chirality·Hassan Y Aboul-EneinSelvakumar Kanthiah

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