Recent developments and future prospects of antimicrobial metabolites produced by endophytes

Microbiological Research
Hongsheng YuLuping Qin

Abstract

Endophytes, found ubiquitous in all plant species in the world, contribute to their host plants by producing plenty of substances that provide protection and ultimately survival value to the plant. Many researches have proven that endophyte is a new and potential source of novel natural products for exploitation in modern medicine, agriculture and industry. So far, a great number of novel natural products possessing antimicrobial activities have been isolated from endophytes. It is believed that screening for antimicrobial compounds from endophytes is a promising way to overcome the increasing threat of drug resistant strains of human and plant pathogen. Antimicrobial metabolites isolated from endophytes belong to diverse structural classes, including: alkaloids, peptides, steroids, terpenoids, phenols, quinones, and flavonoids. In this review, many well-studied areas are presented and examples will be given to discuss the structure of compounds isolated from endophytes extracts with antimicrobial activities and show the wide variety of approaches taken within the field. These achievements would provide the opportunity to utilize endophytes as a new source for production of antibiotics.

References

Sep 8, 2001·Natural Product Reports·R X Tan, W X Zou
Oct 5, 2001·Journal of the American Chemical Society·S F BradyJ Clardy
Dec 11, 2003·Microbiology and Molecular Biology Reviews : MMBR·Gary Strobel, Bryn Daisy
Feb 28, 2004·Journal of Natural Products·Gary StrobelJames Harper
Oct 21, 2006·FEMS Immunology and Medical Microbiology·Souwalak PhongpaichitJariya Sakayaroj
Oct 24, 2007·Phytochemistry·Vatcharin RukachaisirikulKanyawim Kirtikara
May 23, 2008·Phytochemistry·Wipapan PongcharoenWalter C Taylor
Aug 13, 2008·Bioorganic & Medicinal Chemistry·Erwei LiYongsheng Che
Oct 3, 2008·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lei GuoLu-Ping Qin
Feb 28, 2009·Bioorganic & Medicinal Chemistry Letters·Jian-Chun QinAn-Ling Zhang
Mar 24, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Surasak LimsuwanOliver Kayser
May 1, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Li-Li XuLu-Ping Qin

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Citations

Jun 25, 2013·Applied Microbiology and Biotechnology·Cheng-Jian ZhengLu-Ping Qin
Oct 12, 2012·World Journal of Microbiology & Biotechnology·Bita ZaferanlooEnzo A Palombo
Jan 8, 2011·Journal of Natural Medicines·Pei-Xin SunLu-Ping Qin
Jan 1, 2013·The Journal of Microbiology·Luisa CabezasSilvia Restrepo
Apr 19, 2012·The Journal of Antibiotics·János Bérdy
Jun 21, 2014·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Elissandro Fonseca Dos BanhosPatrícia Melchionna Albuquerque
Dec 3, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Haq Nawaz BhattiMuhammad Iqbal Choudhary
Dec 26, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ling-Shang WuTing Han
Jan 7, 2016·Frontiers in Microbiology·Luiz F BianchiniEdvaldo A R Rosa
Feb 26, 2011·Biotechnology Research International·Mariana Recco PimentelGláucia Maria Pastore
May 23, 2015·Frontiers in Microbiology·Irailton Prazeres Dos SantosVera Lucia de Menezes Lima
Mar 21, 2015·Biotechnology Letters·Jutta Ludwig-Müller
Apr 10, 2013·Orvosi hetilap·János Bérdy
Jun 7, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Andrea CochisLia Rimondini
May 10, 2016·Journal of Agricultural and Food Chemistry·Marbella Claudia García-MéndezMartha Lydia Macías-Rubalcava
Mar 9, 2017·The Journal of Antibiotics·Atsuko Matsumoto, Yōko Takahashi
Apr 15, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Anna LeonovVladimir I Titorenko
Sep 6, 2017·Biotechnology and Applied Biochemistry·Wei-Bin WuJian-Zhong Huang
Oct 20, 2012·Chemistry : a European Journal·Christian M Gampe, Erick M Carreira
Jul 7, 2018·Journal of Applied Microbiology·Karla Bianca de Almeida LopesGiuliano Degrassi
Nov 10, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jianglin ZhaoJingguo Wang
Jan 21, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jianglin ZhaoLigang Zhou
May 30, 2019·Journal of Fungi·Rufin Marie Kouipou Toghueo, Fabrice Fekam Boyom
Jan 7, 2020·Current Drug Metabolism·Syed Sayeed AhmadMohammad Amjad Kamal
Aug 9, 2013·Natural Product Reports·Curtis J Henrich, John A Beutler

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