Recent developments in idiopathic intracranial hypertension (IIH)

Seminars in Ophthalmology
James Goodwin

Abstract

Idiopathic intracranial hypertension is a disease with a predilection for young obese women. The most common symptoms are headache, transient visual obscuration and pulsatile tinnitus. The only focal neurologic finding is false-localizing 6th cranial nerve palsy. Papilledema is usually present and this can lead to optic atrophy with progressive permanent visual loss. The earliest visual loss is constriction of peripheral visual field, usually starting with the inferior nasal quadrant. Numerous theories have been entertained as to the pathogenesis but this still remains an open controversy. The most prevalent current theories involve increased resistance to cerebrospinal fluid reabsorption at the arachnoid granulations, either from intrinsic disease in the granulations or secondary to elevated pressure in the dural venous sinuses into which the cerebrospinal fluid is absorbed across the granulations. The syndrome of idiopathic intracranial hypertension was long ago recognized as a complication of recurrent otitis media with resultant thrombosis of the transverse and sigmoid dural venous sinuses. Cases secondary to dural venous sinus thrombosis are seldom encountered today because the incidence of chronic otitis is much less than...Continue Reading

References

Apr 1, 1978·Journal of Neurology, Neurosurgery, and Psychiatry·J Ekstedt
May 1, 1975·Acta paediatrica Scandinavica·K E AnderssonG Wettrell
Aug 1, 1988·Archives of Neurology·F J DurcanM Wall
Jan 1, 1986·Neuropsychologia·J Risberg
Mar 1, 1987·Archives of Ophthalmology·S L HuppS Frazier-Byrne
Dec 22, 1973·Lancet·A BertlerG Wettrell
Mar 2, 1974·Lancet·G D Schott, D Holt
Sep 5, 1970·British Medical Journal·B G Neville, J Wilson
Jan 1, 1970·Archives of Neurology·M H Feldman, N S Schlezinger
Apr 1, 1970·Journal of Neurosurgery·M H Weiss, F E Nulsen
Jan 1, 1971·Brain : a Journal of Neurology·K C HayesT P Faherty
Oct 1, 1966·Journal of Neurosurgery·R C RubinD P Rall
Feb 1, 1983·Neurosurgery·T IwabuchiM Yamashita
May 1, 1993·Archives of Ophthalmology·T C Spoor, J G McHenry
Jun 1, 1996·Neurology·E R EggenbergerS Vitale
Sep 26, 1997·Neurology·R A BurgettA Kawasaki
May 11, 1999·Annals of Surgery·H J SugermanE L Sugerman
Jan 29, 2002·Lancet·J Nicholas P HigginsJohn D Pickard
Jul 3, 2002·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·I JohnstonG Parker
Nov 29, 2002·Neurology·Deborah I Friedman, Daniel M Jacobson
Sep 1, 1956·Neurology·L M DAVIDOFF
Jun 1, 1964·JAMA : the Journal of the American Medical Association·A E WALKER, J J ADAMKIEWICZ
Apr 11, 2006·Neurosurgical Focus·I Johnston

Citations

Apr 25, 2008·Seminars in Ophthalmology·Ronald HammersWalter M Jay
Jun 15, 2010·Seminars in Pediatric Neurology·Ann Pakalnis, Jack Gladstein
Jul 16, 2010·Optometry : Journal of the American Optometric Association·Marisa A PerezNorman J Schatz
Aug 5, 2008·Journal of Neuroimmunology·Alexandra J SinclairSaaeha Rauz
Oct 25, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nathalie GodefroidOlivier Devuyst
Jun 30, 2009·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Ashley D MowlJudith Klein
Oct 10, 2007·Acta Neurologica Scandinavica·N CelebisoyO Akyürekli
Feb 1, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Alki LiasisKen K Nischal
Dec 4, 2013·International Ophthalmology Clinics·Jason Zhang, Rod Foroozan
Jul 6, 2019·The Journal of International Medical Research·Ping GuoWuqing Wang

Related Concepts

Ophthalmology Specialty
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