Recent developments in nuclear magnetic resonance spectroscopy

Science
G C Levy, D J Craik

Abstract

Nuclear magnetic resonance spectroscopy is a powerful and versatile technique that yields information related to molecular structure, interactions, and dynamics. Methods are currently being developed for real-time monitoring of metabolic processes in vivo and for noninvasive detection of disease and abnormality in living animals. Other nuclear magnetic resonance techniques are providing entirely new approaches for analyses of complex chemical systems. The increased power and popularity of nuclear magnetic resonance spectroscopy today are due to many developments in instrumentation and methods that have occurred over the 35-year history of the technique. The most important single advance, particularly in recent years, has been increased sensitivity. Concurrent improvements in effective spectral resolving power and an array of new methods and applications have also contributed to elevating nuclear magnetic resonance spectroscopy to its present position as one of the premier analytical techniques.

References

May 1, 1978·Die Naturwissenschaften·R DamadianJ A Koutcher
Jul 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·R A Komoroski, A Allerhand
Mar 19, 1971·Science·R Damadian
May 28, 1981·The New England Journal of Medicine·B D RossJ Falconer-Smith
Jul 22, 1980·Biochemistry·M E Hogan, O Jardetzky

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Citations

Mar 21, 2008·Journal of Pharmaceutical Sciences·Andria L Skinner, Jennifer S Laurence
Jan 1, 1989·The Journal of Surgical Research·A W BoddieL Dennis
Aug 1, 1982·Journal of Toxicology. Clinical Toxicology·G D PaulsonV J Feil

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