Recent developments of 2-aminothiazoles in medicinal chemistry

European Journal of Medicinal Chemistry
Debasis DasMoumita Bairagi

Abstract

The 2-aminothiazole (2-AT) core is an active pharmacophore and used in medicinal chemistry and drug discovery research. A number of drugs with 2-AT core are in the market, e.g. Famotidine, Cefdinir, Meloxcam etc. Recently, 2-AT core has been explored for many more important therapeutic areas and identified new 2-aminothiazoles with anticancer, antitumor, antidiebatic and anticonvulsant activity. In this review, we discuss the newly identified and developed 2-aminothiazoles in recent years and their use in medicinal chemistry and pharmacology.

References

Oct 1, 1995·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·G EngelhardtC Schnitzler
Apr 19, 2000·Journal of Clinical Psychopharmacology·C DeBattistaA F Schatzberg
Jul 25, 2000·European Journal of Medicinal Chemistry·G Turan-ZitouniK Erol
May 23, 2002·Clinical Therapeutics·David R P Guay
Dec 21, 2006·Bioorganic & Medicinal Chemistry·Ravindra K RawalErik De Clercq
Dec 1, 2007·Nature Reviews. Drug Discovery·Erik De Clercq
Feb 22, 2008·European Journal of Medicinal Chemistry·Nisha SinghAshok Kumar
Apr 9, 2008·European Journal of Medicinal Chemistry·Faizul AzamOm Prakash
May 10, 2008·Bioorganic & Medicinal Chemistry·Kamelia M AminYasmin A Al-Eryani
Jul 8, 2008·European Journal of Medicinal Chemistry·Omar KouatlyPhaedra Eleftheriou
Aug 29, 2009·Bioorganic & Medicinal Chemistry Letters·Zong-Ying LiuDavid W Boykin
Dec 25, 2009·Journal of Virology·Sina GhaemmaghamiStanley B Prusiner
Feb 2, 2010·European Journal of Medicinal Chemistry·Nadeem Siddiqui, Waquar Ahsan
Jan 21, 2011·Journal of Medicinal Chemistry·Alejandra Gallardo-GodoyAdam R Renslo
Jun 30, 2011·European Journal of Medicinal Chemistry·Afsheen ArshadAnis Safirah Mohd Zahariluddin
Oct 4, 2011·Talanta·Susanne NussbaumerSandrine Fleury-Souverain
Jan 1, 2014·Bioorganic & Medicinal Chemistry Letters·Faith MjambiliKelly Chibale
Mar 1, 2014·Nature Reviews. Drug Discovery·Matthias Dobbelstein, Ute Moll
Aug 1, 2014·Future Medicinal Chemistry·J Willem M Nissink, Sam Blackburn
Aug 26, 2014·Bioorganic & Medicinal Chemistry·Dominik VogtHolger Stark
Oct 12, 2014·European Journal of Medicinal Chemistry·Parameshwar Makam, Tharanikkarasu Kannan
Dec 30, 2014·European Journal of Medicinal Chemistry·Chandra Bhushan MishraManisha Tiwari
Jan 7, 2015·Journal of Medicinal Chemistry·Shane M DevineMartin J Scanlon
Mar 12, 2015·Chemical & Pharmaceutical Bulletin·Joanna StefanskaGiuseppina Sanna
May 3, 2015·European Journal of Medicinal Chemistry·Adile AyatiAlireza Foroumadi

❮ Previous
Next ❯

Citations

Aug 11, 2017·Future Medicinal Chemistry·Wei-Wei Gao, Cheng-He Zhou
Oct 24, 2019·Mini Reviews in Medicinal Chemistry·Jilei WangJingyong Sun
Sep 28, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Pin-Kuei FuJen-Kun Chen
Jun 3, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mehlika Dilek AltıntopAhmet Özdemir
Nov 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mara TomassettiEnrico Marcantoni
Jul 7, 2019·European Journal of Medicinal Chemistry·Jitendra NalawadePravin C Mhaske
Nov 6, 2020·European Journal of Medicinal Chemistry·Yichao WanZilong Tang
Feb 27, 2021·Drug Design, Development and Therapy·Sobhi M GomhaHuda K Mahmoud
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mohamed Farouk ElsadekMohamed Fawzi Farahat
Jun 17, 2018·European Journal of Medicinal Chemistry·Adileh AyatiAlireza Foroumadi
Jan 18, 2018·European Journal of Medicinal Chemistry·Adileh AyatiAlireza Foroumadi
Apr 27, 2021·Chemical Research in Toxicology·Chaitanya K JaladankiPrasad V Bharatam
Jul 26, 2021·Chemico-biological Interactions·Arsênio Rodrigues OliveiraAna Cristina Lima Leite
Sep 19, 2020·Current Topics in Medicinal Chemistry·Zhen ZhangQing-Shan Li
Nov 22, 2018·The Journal of Organic Chemistry·Stepan HavelBenoit Carbain
Dec 21, 2017·ACS Medicinal Chemistry Letters·Ying-Ying ChenCheng-He Zhou
Aug 31, 2020·Chemico-biological Interactions·Žiga Jakopin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Related Papers

Clinical and Experimental Neurology
M J Eadie
Monographs in Neural Sciences
S Rump
JAMA : the Journal of the American Medical Association
F E Dreifuss
© 2022 Meta ULC. All rights reserved