Recent developments of microfluidics as a tool for biotechnology and microbiology

Current Opinion in Biotechnology
Ott SchelerPiotr Garstecki

Abstract

Academic microfluidics has decisively shifted in recent years from the research on phenomenology and proof-of-concept fluidic functionalities to the developments oriented at applications with biology, medicine and biotechnology in prime focus. Significant efforts are made to demonstrate that microfluidics can be used in unspecialized laboratories to perform previously mundane tasks faster and easier, or to venture into new research areas that were unavailable or unattractive when only classical means of microbiology or biotechnology were employed. Here we review a variety of biological experiments recently performed in microfluidic assays. We categorize the microfluidic systems by the key role they play in the biological experiments as: (i) controlled reaction chambers, (ii) high-throughput arrays, or (iii) micro-positioning systems. We also discuss the outlook for further development and applications of microfluidics in biological sciences.

Citations

Jan 30, 2020·Micromachines·Dmitry BelyaevGianaurelio Cuniberti
Feb 6, 2019·Journal of Cell Science·Kristina A Ganzinger, Petra Schwille
Dec 15, 2019·Micromachines·Shuxing LvXuguo Sun
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marek Trojanowicz
Jan 26, 2021·Advanced Materials·Joudi MaskounHilmi Volkan Demir
Dec 19, 2020·Nanomaterials·Peipei ZhouJianhua Zhou
May 1, 2021·Nanomaterials·Rui VitorinoVáclav Kašička
Jun 5, 2021·Biomicrofluidics·Jyoti P GurungMatthew A B Baker
Jun 22, 2021·Frontiers in Microbiology·María A Sánchez-Romero, Josep Casadesús
Dec 14, 2021·Accounts of Chemical Research·Kuangwen HsiehTza-Huei Wang

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