Recent innovations in perfusion and cardiopulmonary bypass for neonatal and infant cardiac surgery

Translational Pediatrics
David SturmerMing-Sing Si

Abstract

The development and refinement of cardiopulmonary bypass (CPB) has made the repair of complex congenital heart defects possible in neonates and infants. In the past, the primary goal for these procedures was patient survival. Now that substantial survival rates have been achieved for even the most complex of repairs in these patients, focus has been given to the reduction of morbidity. Although a necessity for these complex neonatal and infant heart defect repairs, CPB can also be an important source of perioperative complications. Recent innovations have been developed to mitigate these risks and is the topic of this review. Specifically, we will discuss improvements in minimizing blood transfusions, CPB circuit design, monitoring, perfusion techniques, temperature management, and myocardial protection, and then conclude with a brief discussion of how further systematic improvements can be made in these areas.

Citations

Jul 8, 2020·Vox Sanguinis·Rebecca CardiganStephen Thomas
Mar 4, 2020·NeoReviews·Timothy W Pettitt
Oct 21, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ben GelbartWarwick Butt
Jan 15, 2020·Cardiology in Review·Daniel PeckTarek Alsaied
Apr 9, 2021·Transfusion·Iñigo Romon, Miguel A Cortes
Nov 18, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Li Ying Koh, Nian Chih Hwang

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