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Recent progress in synthetic and biological studies of GPI anchors and GPI-anchored proteins

Current Opinion in Chemical Biology

Oct 17, 2013

Shichong YuQiuye Wu

Abstract

Covalent attachment of glycosylphosphatidylinositols (GPIs) to the protein C-terminus is one of the most common posttranslational modifications in eukaryotic cells. In addition to anchoring surface proteins to the cell membrane, GPIs also have many other important biological functions, ...read more

Mentioned in this Paper

GPI-Linked Proteins
Covalent Interaction
Post-Translational Protein Processing
Protein C, human
Protein C Measurement
Protein Biosynthesis
Protein C Antigen Measurement
Glycosylphosphatidylinositol Deficiency
PROC gene
Phosphatidylinositol Glycan
1
53
Paper Details
References
  • References53
  • Citations11
12345...
  • References53
  • Citations11
12

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Recent progress in synthetic and biological studies of GPI anchors and GPI-anchored proteins

Current Opinion in Chemical Biology

Oct 17, 2013

Shichong YuQiuye Wu

PMID: 24128440

DOI: 10.1016/j.cbpa.2013.09.016

Abstract

Covalent attachment of glycosylphosphatidylinositols (GPIs) to the protein C-terminus is one of the most common posttranslational modifications in eukaryotic cells. In addition to anchoring surface proteins to the cell membrane, GPIs also have many other important biological functions, ...read more

Mentioned in this Paper

GPI-Linked Proteins
Covalent Interaction
Post-Translational Protein Processing
Protein C, human
Protein C Measurement
Protein Biosynthesis
Protein C Antigen Measurement
Glycosylphosphatidylinositol Deficiency
PROC gene
Phosphatidylinositol Glycan
1
53

Feeds With Similar Papers

Biomaterial Engineering

Advances in biomaterial engineering have permitted the development of sophisticated drug-releasing materials with a biomimetic 3D support that allow a better control of the microenvironment of transplanted cells. Here is the latest research.

GPI Anchoring

Glycosylphosphatidylinositol (GPI) is a glycolipid anchor for several cell-surface proteins that play a role in various biological processes, including signal transduction, prion disease pathogenesis, and immune response. Here is the latest research.

Related Papers

Angewandte Chemie

Chemical biology of glycosylphosphatidylinositol anchors(opens in new tab)

Angewandte ChemieOctober 23, 2012
Yu-Hsuan TsaiPeter H Seeberger
Paper Details
References
  • References53
  • Citations11
12345...
  • References53
  • Citations11
12

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