Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
Chin Siang KueHong Boon Lee

Abstract

BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen (1O2) from molecular oxygen, leading to tissue damage in the photoirradiated region. Despite their extraordinary photophysical characteristics, they are not featured in clinical photodynamic therapy. This review discusses the recent advances in the design and/or modifications of BODIPYs since 2013, to improve their potential in photodynamic cancer therapy and related areas.

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Citations

Jul 12, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Hasrat AliJohan E van Lier
Jul 10, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Nuray Esra AksakalFatma Yuksel
Aug 10, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Arno WieheMathias O Senge
Sep 10, 2019·Physical Chemistry Chemical Physics : PCCP·Ruth Prieto-MonteroSylvie Lacombe
Nov 28, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Minoru YamajiHideki Okamoto
Feb 14, 2020·Physical Chemistry Chemical Physics : PCCP·Barry ManghamNeil R Champness
Oct 3, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Gregory D SuttonThomas S Teets
Jun 26, 2020·Chemistry : a European Journal·Jasper DeckersWouter Maes
Mar 22, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Debao LiuNuonuo Zhang
Apr 3, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Felix Y Telegin, Yuriy S Marfin
Apr 13, 2021·Inorganic Chemistry·Vanitha RamuAkhil R Chakravarty
Apr 8, 2021·ACS Applied Materials & Interfaces·Young Hun JungJang Hyuk Kwon
Apr 30, 2021·European Journal of Medicinal Chemistry·Arnab BhattacharyyaAkhil R Chakravarty
May 27, 2021·Chemical Communications : Chem Comm·Suay DartarMustafa Emrullahoglu
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kseniya A MariewskayaAlexey V Ustinov
Aug 21, 2019·The Journal of Physical Chemistry. B·Meredith M OgleAngel A Martí
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Feb 11, 2020·The Journal of Physical Chemistry. a·Sebastian RadunzUte Resch-Genger
Nov 2, 2018·Journal of the American Chemical Society·Mingle LiXiaojun Peng
Sep 24, 2021·Chemistry : a European Journal·Karolina MaleckaitėAurimas Vyšniauskas
Jan 7, 2022·Inorganic Chemistry·Aarti UpadhyayAkhil R Chakravarty

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Methods Mentioned

BETA
circular dichroism
fluorescence imaging
confocal microscopy
xenograft
surface plasmon resonance
flow cytometry
flow
fluorescence microscopy

Clinical Trials Mentioned

NCT03346304
NCT02916745
NCT00436553

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