Recent substance intake among patients admitted to acute psychiatric wards: physician's assessment and on-site urine testing compared with comprehensive laboratory analyses

Journal of Clinical Psychopharmacology
Jon MordalJørgen Gustav Bramness

Abstract

This cross-sectional study of acute psychiatric admissions compared physicians' assessments of recent substance intake and on-site urine testing with comprehensive laboratory drug analyses. The sample comprised 325 consecutive admissions from 2 acute psychiatric wards. Physicians on call were asked to judge if the patient had recently taken benzodiazepines, opiates, alcohol, amphetamines, cannabis, or cocaine. Blood and urine samples were obtained and analyzed with chromatographic laboratory methods for a wide range of substances. A routine on-site urine screening test was performed in 92 of the cases. Physicians' assessments and on-site urine testing were compared with the reference standard of laboratory analyses. The sensitivity of the physician's assessment was highest for amphetamines (76%), followed by benzodiazepines (61%), opiates (57%), cannabis (55%), and cocaine (50%), whereas specificity was greater than 90% for all substances. The sensitivity of the on-site test ranged from 76% for amphetamine to 97% for cannabis, and specificity ranged from 82% for cannabis to 100% for cocaine. The study indicates clinical underdetection of recent substance intake among acute psychiatric admissions. On-site urine testing identifie...Continue Reading

References

Jan 1, 1991·The American Journal of Drug and Alcohol Abuse·B WoodwardS M Mirin
Mar 1, 1989·Hospital & Community Psychiatry·J AnanthM Miller
Jul 1, 1994·The American Journal of Psychiatry·M J AlbaneseA F Schatzberg
Feb 1, 1997·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·J S OlshakerT O Stair
Mar 1, 1997·Psychiatric Services : a Journal of the American Psychiatric Association·C A ClaassenA J Rush
May 20, 1999·Journal of Psychoactive Drugs·J RachBeiselJ Gearon
Jan 27, 2000·Psychiatric Services : a Journal of the American Psychiatric Association·M J SchillerS L Batki
May 29, 2000·The British Journal of Psychiatry : the Journal of Mental Science·M Soyka
Aug 5, 2000·The American Journal of Emergency Medicine·R R ReevesR Kimble
Jan 6, 2001·Acta Psychiatrica Scandinavica·S S HansenA Bertelsen
Jul 24, 2001·Scandinavian Journal of Clinical and Laboratory Investigation·A LeinoP Lillsunde
Nov 24, 2004·Biological Psychiatry·John A Renner
Apr 18, 2006·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·M A BjornaasD Jacobsen
Jun 29, 2007·European Psychiatry : the Journal of the Association of European Psychiatrists·Renaud de BeaurepaireRobert Molimard
Jul 1, 2008·Psychiatry and Clinical Neurosciences·Mario AmoreDomenico Berardi
May 15, 2009·Journal of Clinical Psychopharmacology·Gunnhild BagøienOlav Spigset
Jun 12, 2009·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Milton Tenenbein

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Citations

Jan 23, 2013·Journal of Substance Abuse Treatment·Julie DupouyMaryse Lapeyre-Mestre
Jul 22, 2014·Scandinavian Journal of Clinical and Laboratory Investigation·Olof BeckPeter Hulten
Apr 14, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Odd Martin VallersnesKnut Erik Hovda
Dec 21, 2018·Drug Testing and Analysis·Fabian PichtMichael Böttcher
Nov 13, 2018·Journal of Addiction Medicine·Bhanu Prakash KollaTerry D Schneekloth
Aug 29, 2013·Drug Testing and Analysis·Dayong Lee, Marilyn A Huestis
Mar 23, 2011·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Jørg Mørland
Apr 3, 2021·Currents in Pharmacy Teaching & Learning·Karen E MoellerBrittany L Melton

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