Recent technological advancements in tuberculosis diagnostics - A review

Biosensors & Bioelectronics
Shagun Gupta, Vipan Kakkar

Abstract

Early diagnosis and on-time effective treatment are indispensable for Tuberculosis (TB) control - a life threatening infectious communicable disease. The conventional techniques for diagnosing TB normally take two to three weeks. This delay in diagnosis and further increase in detection complexity due to the emerging risks of XDR-TB (Extensively drug Resistant-TB) and MDR-TB (Multidrug Resistant-TB) are evoking interest of researchers in the field of developing rapid TB detection techniques such as biosensing and other point-of-care (POC) techniques. Biosensing technologies along with the collaboration with nanotechnology have enormous potential to boost the MTB detection and for overall management in clinical diagnosis. A diverse range of portable, sensitive and rapid biosensors based on different signal transducer principles and with different biomarkers detection capabilities have been developed for TB detection in the early stages. Further, a lot of progress has been achieved over the years in developing various point-of-care diagnostic tools including non-molecular methods and molecular techniques. The objective of this study is to present a succinct review of the available TB detection techniques that are either in use or...Continue Reading

Citations

Sep 26, 2019·Critical Reviews in Biotechnology·Behrouz GolichenariJavad Behravan
Jul 30, 2020·Biomedical Microdevices·Seong-Joong KahngJae-Hyun Chung
Sep 13, 2018·Current Medicinal Chemistry·Le Minh Tu PhanTae Jung Park
Dec 5, 2018·Biosensors & Bioelectronics·Xuanying LiZhenzhong Guo
Aug 27, 2019·Microbial Pathogenesis·Shagun GuptaIndu Bhushan
Apr 12, 2021·BMC Infectious Diseases·Xun-Jie CaoXu-Guang Guo
Apr 13, 2021·Frontiers of Environmental Science & Engineering·Jinbiao MaQian Zhang
Jun 9, 2021·The Indian Journal of Tuberculosis· KajalRohit Rai
Jan 14, 2022·Analytical Methods : Advancing Methods and Applications·Jinbiao MaMin Wu

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