Recent trends (2016-2017) in the treatment of inflammatory bowel disease

Annals of Gastroenterological Surgery
Tadahiko MasakiHiroyoshi Matsuoka

Abstract

Prevalence of inflammatory bowel disease (IBD), ulcerative colitis and Crohn's disease has dramatically increased in Asian countries in the last three decades. In this period, many new medical therapies were introduced for the treatment of IBD, such as immunosuppressants, anti-tumor necrosis factor agents, leukocyte apheresis, anti-integrin antibody, and so on, which have contributed to induce remission and to reduce complications in IBD. As for surgical techniques for Crohn's disease, a stapled functional end-to-end anastomosis and conventional end-to-end anastomosis have similar perianastomotic recurrence rate and reoperation rate. Prospective randomized controlled studies which compare Kono-S anastomosis and stapled side-to-side anastomosis are ongoing. Variant two-stage ileal pouch anal anastomosis (IPAA) and transanal IPAA are new concepts for surgical treatment of ulcerative colitis. Various endoscopic procedures, such as balloon dilation for stenosis or stricture, endoscopic fistulotomy, injection of filling agents, and clipping for fistulas or perforations will be new options in the treatment of Crohn's disease. Adverse effects of preoperative treatments on postoperative complications should also be taken into account t...Continue Reading

References

Jun 1, 1993·American Journal of Hematology·P E DrakosR Or
Aug 19, 2000·Diseases of the Colon and Rectum·T YamamotoM R Keighley
Dec 11, 2002·Diseases of the Colon and Rectum·Ian LindseyBruce D George
May 21, 2003·International Journal of Colorectal Disease·Damian García-OlmoLuis García-Sancho
Feb 24, 2004·Diseases of the Colon and Rectum·Rasmy LoungnarathJames W Fleshman
Jun 14, 2005·Alimentary Pharmacology & Therapeutics·V VittonJ C Grimaud
Jul 5, 2005·World Journal of Gastroenterology : WJG·Takayuki Yamamoto
Aug 13, 2008·Expert Opinion on Biological Therapy·Damian Garcia-OlmoDolores Herreros
Jun 9, 2009·Diseases of the Colon and Rectum·Robin S McLeodUNKNOWN Investigators of the CAST Trial
Feb 25, 2010·Gastroenterology·Jean-Charles GrimaudUNKNOWN Groupe d'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif
Oct 18, 2011·Bone Marrow Transplantation·J A SnowdenUNKNOWN Paediatric Diseases Working Party (PDWP)
Apr 14, 2012·Journal of Gastroenterology and Hepatology·Lani PrideauxSiew C Ng
May 15, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Alessandro FicheraToru Kono
Jan 10, 2013·Annals of Surgery·Victor Warren FazioSean T Martin
Mar 26, 2013·Journal of Crohn's & Colitis·Vincent BillioudLaurent Peyrin-Biroulet
Feb 12, 2015·Surgical Endoscopy·Marta M TasendeAntonio M Lacy
Feb 27, 2015·Techniques in Coloproctology·R MennigenE Rijcken
Aug 20, 2015·Inflammatory Bowel Diseases·Edward SheltonVijay Yajnik
Sep 12, 2015·Alimentary Pharmacology & Therapeutics·P S MorarUNKNOWN Crohn's Stricture Study (CroSS) Group
Dec 24, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Toru KonoMikihiro Fujiya
Feb 20, 2016·Gut·Jean-Frédéric ColombelBrian G Feagan
Mar 8, 2016·Gastroenterology·Miguel RegueiroUNKNOWN PREVENT Study Group
Dec 14, 2016·The American Journal of Gastroenterology·Mathurin FumeryUNKNOWN REMIND study group investigators
Apr 15, 2017·United European Gastroenterology Journal·Anna Rueda GuzmánMartin Goetz
Jun 9, 2017·Diseases of the Colon and Rectum·Andreas Nordholm-CarstensenKikke Hagen
Jul 19, 2017·The American Journal of Gastroenterology·Akihiro YamadaAtsushi Sakuraba
Aug 26, 2017·Gastroenterology Clinics of North America·Siddharth Singh, Geoffrey C Nguyen
Sep 1, 2017·Inflammatory Bowel Diseases·Amy L LightnerKellie L Mathis
Sep 9, 2017·Journal of Gastroenterology·Motoi UchinoUNKNOWN a research grant on intractable disease affiliated with the Japan Ministry of Health Labor Welfare

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Citations

Feb 26, 2020·Intestinal research·Ronald KellerThomas Klag
May 18, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A AlshanttiS R Brown
Mar 3, 2020·Frontiers in Cellular and Infection Microbiology·Amin JablaouiMoez Rhimi
Nov 19, 2019·Reviews on Recent Clinical Trials·Basant K Puri
Nov 10, 2020·Clinics in Colon and Rectal Surgery·Toru Kono, Alessandro Fichera
Apr 4, 2021·International Journal of Molecular Sciences·Vincent MariauleMoez Rhimi

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Clinical Trials Mentioned

NCT03256240
NCT02631967

Software Mentioned

ADMIRE
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