Recent Trends in Electrochemical Sensors for Vital Biomedical Markers Using Hybrid Nanostructured Materials

Advanced Science
K Koteshwara ReddyHern Kim

Abstract

This work provides a succinct insight into the recent developments in electrochemical quantification of vital biomedical markers using hybrid metallic composite nanostructures. After a brief introduction to the biomarkers, five types of crucial biomarkers, which require timely and periodical monitoring, are shortlisted, namely, cancer, cardiac, inflammatory, diabetic and renal biomarkers. This review emphasizes the usage and advantages of hybrid nanostructured materials as the recognition matrices toward the detection of vital biomarkers. Different transduction methods (fluorescence, electrophoresis, chemiluminescence, electrochemiluminescence, surface plasmon resonance, surface-enhanced Raman spectroscopy) reported for the biomarkers are discussed comprehensively to present an overview of the current research works. Recent advancements in the electrochemical (amperometric, voltammetric, and impedimetric) sensor systems constructed with metal nanoparticle-derived hybrid composite nanostructures toward the selective detection of chosen vital biomarkers are specifically analyzed. It describes the challenges involved and the strategies reported for the development of selective, sensitive, and disposable electrochemical biosensors ...Continue Reading

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Citations

Jul 24, 2020·Sensors·Veronika GajdosovaJan Tkac
Jan 8, 2021·Comprehensive Reviews in Food Science and Food Safety·Wenlei ZhaiMeng Wang
Mar 12, 2021·Biosensors & Bioelectronics·K Yugender GoudK Vengatajalabathy Gobi
Sep 2, 2021·Biomedical Engineering Letters·Jae Hyun KimKyo Seon Hwang

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Methods Mentioned

BETA
biosensor
biosensors
electrophoresis
glycosylation
circular dichroism
fluorescence
light scattering
sandwich
chip
sandwich immunoassay

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