PMID: 9447283Aug 1, 1997Paper

Recent trends in the management of Graves' hyperthyroidism in Japan: opinion survey results, especially on the combination therapy of antithyroid drug and thyroid hormone

Endocrine Journal
T MoriA Matsuda

Abstract

An opinion survey concerning the management of Graves' hyperthyroidism was conducted among the council members of the Japan Thyroid Association. The selection of 3 major treatments by 90 respondents for their patients was 98.6 +/- 4.2% for antithyroid drug (ATD), 7.8 +/- 12.6% for partial thyroidectomy and 5.2 +/- 8.1% for radioiodide. They expressed a movement away from the past trend of surgery because of postoperative complications and unsatisfactory therapeutic results, and they assumed a further reduction in the future. On the other hand, the frequency of radioiodide treatment was not considered to have decreased greatly, and they expected a slight increase in the future. Of the respondents, 65% suggested that hyperthyroidism should be completely cured even if the patient would fall into hypothyroidism. The major reasons for choosing surgery or radioiodide after ATD were the adverse effects of ATD and the age and social backgrounds of the patients. Large goiter size was the 3rd reason for surgery but was a minimal indicator for radioiodide. As for ATD treatment, none of the respondents reported the routine application of any uniform fixed-time therapy protocol. Japanese Graves' patients were shown to be less responsive to ...Continue Reading

Citations

Jun 30, 2000·Endocrinology and Metabolism Clinics of North America·O Alsanea, O H Clark
Jan 22, 2002·Journal of the American College of Surgeons·Kazuo ShimizuShigeo Tanaka
Apr 6, 2001·Thyroid : Official Journal of the American Thyroid Association·P Werga-KjellmanG Wallin
Jul 10, 2004·Thyroid : Official Journal of the American Thyroid Association·Kiminori SuginoKunihiko Ito
Jul 9, 2011·Head & Neck·Murat KaramanArzu Tatlıpınar
Dec 3, 2005·The British Journal of Surgery·S MaedaT Kanematsu
Mar 27, 2019·Endocrinology and Metabolism·Wilmar M Wiersinga

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