Receptive fields of frog retinal ganglion cells: response formation and light-dark-adaptation

The Journal of Physiology
K Donner

Abstract

1. The excitatory and inhibitory receptive field mechanisms of retinal ganglion cells were studied by extracellular recording from the eyecup of Rana temporaria in order to elucidate the nature of adaptational changes in the functioning of the receptive field. 2. The responses to large stimuli were always strongly depressed relative to responses evoked by smaller spots. This was true even in the fully dark-adapted state and at the very lowest stimuli intensities. 3. Threshold measurements confirmed earlier findings, usually revealing the surround only in light-adapted states. However, in more than 10% of fully dark-adapted cells thresholds to large stimuli were significantly elevated. 4. The central summation area of the receptive field was found to shrink with light-adaptation. There was a gradual decrease in diameters, amounting to some 20-30%, from the dark-adapted, rod-determined receptive fields to the cone-determined ones. 5. Adaptation by bleaching and adaptation by backgrounds changed the effects of the surround in different ways. After a rhodopsin bleach the transition from a light-adapted to a dark-adapted situation was seen as an abrupt drop of large-stimulus thresholds at some time during adaptation. Steady backgrou...Continue Reading

Citations

May 15, 2012·Progress in Retinal and Eye Research·Wallace B Thoreson, Stuart C Mangel
Sep 20, 2011·Vision Research·Tom Reuter
Sep 8, 1989·The Journal of Comparative Neurology·W H BaldridgeR G Miller
Dec 1, 1987·Journal of the Optical Society of America. A, Optics and Image Science·A C Aho Orlov OYu
Jun 22, 1987·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S C Mangel, J E Dowling
Sep 4, 2015·Journal of Neurophysiology·Inigo Novales Flamarique, Matt Wachowiak
Jul 31, 2021·The Journal of Experimental Biology·Kristian Donner

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