PMID: 11343923May 10, 2001Paper

Receptor clustering and transmembrane signaling in T cells

Trends in Biochemical Sciences
J R CochranL J Stern

Abstract

T cells are activated via engagement of their cell-surface receptors with molecules of the major histocompatibility complex (MHC) displayed on another cell surface. This process, which is a key step in the recognition of foreign antigens by the immune system, involves oligomerization of receptor components. Recent characterization of the T-cell response to soluble arrays of MHC-peptide complexes has provided insights into the triggering mechanism for T-cell activation.

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Citations

Sep 6, 2002·Journal of Immunological Methods·Thomas O CameronLawrence J Stern
Sep 15, 2001·Trends in Immunology·T O CameronL J Stern
May 1, 2008·Biochemistry·Jonathan A Cooper, Hong Qian
Apr 4, 2006·Nature Reviews. Microbiology·Richard D HaywardKenneth G Campellone
Jun 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·Daisuke ItoKoho Iizuka
Aug 10, 2005·The Journal of Experimental Medicine·Wolfgang W A SchamelBalbino Alarcón
Feb 25, 2005·The Journal of Experimental Medicine·Susan E Levin, Arthur Weiss
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Aug 14, 2019·Immunological Reviews·Wolfgang W SchamelSusana Minguet

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