Rechargeable and LED-activated ZnGa2 O4  : Cr3+ near-infrared persistent luminescence nanoprobes for background-free biodetection

Nanoscale
Zhihao ZhouXueyuan Chen

Abstract

Persistent luminescence nanoparticles (PLNPs) have shown great promise in the field of biomedicine, but are currently limited by the challenge in the synthesis of high-quality PLNPs with bright persistent luminescence and a long afterglow time. Herein, we report a facile strategy for the synthesis of monodisperse, rechargeable and LED-activated ZnGa2O4 : Cr3+ near-infrared (NIR) PLNPs based on a modified solvothermal liquid-solid-solution method. The as-synthesized PLNPs are not only flexible for bioconjugation, but could also circumvent the limitation of the weak persistent luminescence and short afterglow time that most PLNPs confronted owing to their rechargeable capability. It was unraveled that both thermal activation and quantum tunneling mechanisms contributed to the afterglow decay of the PLNPs, and the quantum tunneling was found to dictate the LED-activated afterglow intensity and lasting time. Furthermore, by utilizing the superior excitation-free persistent luminescence, we demonstrated for the first time the application of biotinylated ZnGa2O4 : Cr3+ PLNPs as background-free luminescent nano-bioprobes for sensitive and specific detection of avidin in a heterogeneous assay with a limit of detection down to ∼150 pM, ...Continue Reading

References

Feb 1, 1994·Physical Review. B, Condensed Matter·M CasalboniA A Kaminskii
Sep 2, 2005·Nature·Xun WangYadong Li
Jun 2, 2006·Journal of Nanoscience and Nanotechnology·Wei Chen, Jun Zhang
May 23, 2007·Proceedings of the National Academy of Sciences of the United States of America·Quentin le Masne de ChermontDaniel Scherman
Jun 1, 2011·Angewandte Chemie·Markus Haase, Helmut Schäfer
Jun 7, 2011·Optics Express·Aurélie BessièreDidier Gourier
Jun 28, 2011·Journal of the American Chemical Society·Thomas MaldineyDaniel Scherman
Jan 31, 2015·Chemical Communications : Chem Comm·Wei ZhengXueyuan Chen
Apr 1, 2015·Chemical Communications : Chem Comm·Bhupendra B SrivastavaYuanbing Mao
Apr 8, 2015·Nature Materials·Zhongfu AnWei Huang
Jun 9, 2015·Nanoscale·Jintao KongXueyuan Chen
Nov 5, 2015·Nature Nanotechnology·Bo ZhouXiaogang Liu
Dec 10, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Jian YangXiaojun Wang
Feb 4, 2016·Chemical Society Reviews·Yang LiJianrong Qiu
Jul 12, 2013·Materials·Koen Van den EeckhoutPhilippe F Smet
Mar 14, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·W B DaiQ Y Zhang

❮ Previous
Next ❯

Citations

May 16, 2020·Chemical Communications : Chem Comm·Linna FuQuan Yuan
May 6, 2019·Optics Express·Tianyi LiYanmin Yang
Jan 13, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yaling LinHaomiao Zhu
Mar 10, 2020·Nano-micro Letters·Shuqi WuLianbing Zhang
Jul 21, 2021·Chemical Reviews·W Russ AlgarHyungki Kim
Jul 23, 2021·The Journal of Physical Chemistry Letters·Xiaojun WeiLihong Jing
Aug 10, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Zhijun ZhangBengang Xing
Aug 22, 2020·Inorganic Chemistry·Zhihao ZhouMingying Peng
Sep 25, 2021·Chemical Reviews·Yuyan Jiang, Kanyi Pu
Aug 29, 2021·Angewandte Chemie·Wei ZhengHong Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.