PMID: 6165439May 25, 1981Paper

Reciprocal connections between the lateral hypothalamus and the frontal complex in the rat: electrophysiological and anatomical observations

Brain Research
H Kita, Y Oomura

Abstract

Inputs to rat lateral hypothalamus (LHA) from prefrontal cortex (FC), and vice versa, were studied by intracellular recording, and by retrograde horseradish peroxidase (HRP) method. Stimulation of the FC evoked 3 types of responses: a polysynaptic EPSP-IPSP sequence, IPSPs alone, or antidromic response in LHA neurons. Forty-five per cent of IPSPs were considered to be monosynaptic since the latencies were constant when stimulus intensity was changed. The neurons labeled in the FC following electrophoretic injections of HRP into LHA were located in the medial and sulcal FC. In these cortical areas, not only pyramidal neurons in layer V, but also non-pyramidal neurons in layer VI were labeled. Stimulation of the LHA evoked an EPSP-IPSP sequence, or antidromic response in FC neurons. Some of the fast EPSPs were considered to be monosynaptic. The neurons labeled in the LHA following HRP injection into the FC were either relatively large spherical neurons or small ovoid-shaped neurons. These were distributed diffusely throughout the LHA.

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Citations

Jan 1, 1990·Experimental Brain Research·S G Hardy, S M Mack
Oct 1, 1994·Integrative Physiological and Behavioral Science : the Official Journal of the Pavlovian Society·D F Cechetto
Jan 1, 1988·Physiology & Behavior·Y Oomura
Jan 1, 1983·Neuroscience and Biobehavioral Reviews·M J WaynerH U Aguilar-Baturoni
Dec 14, 1990·Behavioural Brain Research·A S BatuevA P Shutov
Jan 1, 1982·Brain Research Bulletin·H Kita, Y Oomura
Dec 1, 1990·Brain Research Bulletin·L Hernandez, B G Hoebel
Feb 9, 2007·Archives of Histology and Cytology·Takashi Yamamoto
Oct 17, 2007·Journal of Neurosurgery·Sepehr SaniRoy A E Bakay
Apr 1, 1985·Journal of Neurosurgery·E G FischerR Cassady
Jan 28, 2016·Nature Neuroscience·Garret D Stuber, Roy A Wise
Jul 7, 2012·Behavioural Brain Research·Bernadett NagyZoltán Karádi
Apr 10, 1984·The Journal of Comparative Neurology·M Sarter, H J Markowitsch
Jan 28, 1982·Brain Research·A Canedo
Sep 29, 2015·Journal of Developmental Origins of Health and Disease·R Dalle MolleP P Silveira
Dec 19, 2014·The International Journal of Neuropsychopharmacology·Iku Tsutsui-KimuraMitsuhiro Yoshioka

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