PMID: 7026574Aug 1, 1981Paper

Recognition of Bergmann glial and ependymal cells in the mouse nervous system by monoclonal antibody

The Journal of Cell Biology
I SommerM Schachner

Abstract

A monoclonal antibody designated anti-Cl was obtained from a hybridoma clone isolated from a fusion of NS1 myeloma with spleen cells from BALB/c mice injected with homogenate of white matter from bovine corpus callosum. In the adult mouse neuroectoderm, C1 antigen is detectable by indirect immunohistology in the processes of Bergmann glial cells (also called Golgi epithelial cells) in the cerebellum and of Müller cells in the retina, whereas other astrocytes that express glial fibrillary acidic protein in these brain areas are negative for C1. In addition, C1 antigen is expressed in most, if not all, ependymal cells and in large blood vessels, but not capillaries. In the developing, early postnatal cerebellum, C1 antigen is not confined to Bergmann glial and ependymal cells but is additionally present in astrocytes of presumptive white matter and Purkinje cell layer. In the embryonic neuroectoderm, C1 antigen is already expressed at day 10, the earliest stage tested so far. The antigen is distinguished in radially oriented structures in telencephalon, pons, pituitary anlage, and retina. Ventricular cells are not labeled by C1 antibody at this stage. C1 antigen is not detectable in astrocytes of adult or nearly adult cerebella f...Continue Reading

References

Jan 1, 1978·Brain Research Bulletin·C GoridisM Schachner
Jul 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L F Eng, L J Rubinstein
Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·W W FrankeK Weber
Jan 1, 1978·Annual Review of Neuroscience·V S Caviness, P Rakic
Jun 15, 1978·The Journal of Comparative Neurology·D M Landis, R L Sidman
Mar 1, 1978·The American Journal of Anatomy·R J WalshP L Lin
Jul 15, 1978·The Journal of Comparative Neurology·R H Nordlander, M Singer
May 20, 1977·Brain Research·M SchachnerG L Campbell
Jan 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·P Rakic, R L Sidman
Apr 1, 1973·Journal of Cellular Physiology·D S BarkleyD L Wong
May 1, 1972·The Journal of Comparative Neurology·P Rakic
Nov 15, 1973·The Journal of Comparative Neurology·P Rakic, R L Sidman
Jun 1, 1968·The Journal of Comparative Neurology·J E Vaughn, A Peters
Jan 1, 1969·Zeitschrift für Zellforschung und mikroskopische Anatomie·J E Vaughn
Jan 1, 1980·Developmental Biology·M Willinger, M Schachner
Oct 1, 1980·Developmental Biology·C LagenaurM Schachner
Aug 24, 1962·Science·R L SIDMANM M DICKIE
Jan 1, 1962·Zeitschrift für Zellforschung und mikroskopische Anatomie·V M TENNYSON, G D PAPPAS

❮ Previous
Next ❯

Citations

Jan 1, 1983·Anatomy and Embryology·T ShigaY Hirata
Mar 1, 1984·Developmental Biology·P BovolentaC A Mason
Aug 1, 1984·Brain Research·S K PixleyJ de Vellis
Jun 22, 1992·Neuroscience Letters·A C ChangN C Chang
Jan 1, 1983·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M S GhandourJ Clos
Oct 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·S DamjanovichT M Jovin
Mar 1, 1995·Glia·J M Luque, J G Richards
Jun 1, 1982·Immunology Today·C J Barnstable
Jul 1, 1982·Journal of Neurochemistry·M Schachner
Jan 1, 1981·Journal of Supramolecular Structure and Cellular Biochemistry·I Sommer, M Schachner
Nov 7, 2006·The Journal of Veterinary Medical Science·Tomohiro ImagawaMasato Uehara
May 14, 1998·Microscopy Research and Technique·J B GabrionJ P Delaunoy
Jan 1, 1984·Central Nervous System Trauma : Journal of the American Paralysis Association·M E HattenM L Shelanski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Adhesion Molecules in AS

Cell adhesion molecules expressed on the vascular endothelium and circulating leukocytes in response to inflammatory stimuli are implicated in atherosclerosis. Here is the latest research.

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.