Recognizing primary immune deficiency in clinical practice

Clinical and Vaccine Immunology : CVI
Hale YarmohammadiCharlotte Cunningham-Rundles

Abstract

Primary immunodeficiency results in recurrent infections, organ dysfunction, and autoimmunity. We studied 237 patients referred for suspicion of immunodeficiency, using a scoring system based on clinical information. The 113 patients with immunodeficiency had higher scores and more episodes of chronic illnesses and were more likely to have neutropenia, lymphopenia, or splenomegaly.

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