Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals

Chemical Senses
Kathrin OhlaNirupa Chaudhari

Abstract

The gustatory system encodes information about chemical identity, nutritional value, and concentration of sensory stimuli before transmitting the signal from taste buds to central neurons that process and transform the signal. Deciphering the coding logic for taste quality requires examining responses at each level along the neural axis-from peripheral sensory organs to gustatory cortex. From the earliest single-fiber recordings, it was clear that some afferent neurons respond uniquely and others to stimuli of multiple qualities. There is frequently a "best stimulus" for a given neuron, leading to the suggestion that taste exhibits "labeled line coding." In the extreme, a strict "labeled line" requires neurons and pathways dedicated to single qualities (e.g., sweet, bitter, etc.). At the other end of the spectrum, "across-fiber," "combinatorial," or "ensemble" coding requires minimal specific information to be imparted by a single neuron. Instead, taste quality information is encoded by simultaneous activity in ensembles of afferent fibers. Further, "temporal coding" models have proposed that certain features of taste quality may be embedded in the cadence of impulse activity. Taste receptor proteins are often expressed in nono...Continue Reading

References

Dec 1, 1975·The Journal of General Physiology·M SatoS Yamashita
Oct 1, 1991·Journal of Neurophysiology·K Nakamura, R Norgren
Jun 1, 1991·Journal of Neurophysiology·M E Frank
Apr 1, 1990·Journal of Neurophysiology·H Nishijo, R Norgren
Aug 1, 1987·The Journal of Comparative Neurology·D F Cechetto, C B Saper
Jan 1, 1989·Comparative Biochemistry and Physiology. A, Comparative Physiology·K Tonosaki, L M Beidler
Jun 1, 1989·Journal of Neurophysiology·T YamamotoR Kitamura
Jun 1, 1988·Journal of Neurophysiology·P M Di Lorenzo
Feb 8, 1986·The Journal of Comparative Neurology·T C PritchardR Norgren
Jan 1, 1984·Progress in Neurobiology·T Yamamoto
Jan 1, 1984·Experimental Brain Research·S AzumaY Kawamura
Oct 1, 1983·Journal of Neurophysiology·M E FrankT P Hettinger
Nov 10, 1983·The Journal of Comparative Neurology·M C Whitehead, M E Frank
Apr 1, 1984·Journal of Neurophysiology·T YamamotoY Kawamura
Mar 1, 1981·Journal of Neurophysiology·T Nagai, K Ueda
Sep 1, 1980·Journal of Neurophysiology·T YamamotoY Kawamura
Dec 1, 1994·Physiology & Behavior·G Hellekant, Y Ninomiya
Jun 1, 1994·Journal of Neurophysiology·R P EricksonM A Woodbury
Aug 1, 1996·Journal of Neurophysiology·J D Victor, K P Purpura
Jun 9, 1998·Annals of the New York Academy of Sciences·J D Victor, K P Purpura
Aug 17, 1999·Current Opinion in Neurobiology·D V Smith, S J St John
Jan 25, 2000·American Journal of Physiology. Gastrointestinal and Liver Physiology·D B KatzS A Simon
Apr 13, 2000·Cell·E AdlerC S Zuker
Apr 15, 2000·Nature·H MatsunamiL B Buck
Jun 16, 2000·Physiology & Behavior·D V SmithJ D Boughter
Jun 16, 2000·Physiology & Behavior·P M Di Lorenzo
Feb 13, 2001·Trends in Cognitive Sciences·J I. Gold, M N. Shadlen
Feb 27, 2001·Science·A Caicedo, S D Roper
Mar 15, 2001·Journal of Neurophysiology·J O'DohertyF McGlone
Aug 15, 2001·Current Opinion in Neurobiology·H D Abarbanel, M I Rabinovich
Aug 18, 2001·Cell·G NelsonC S Zuker
Mar 15, 2002·Nature·Greg NelsonCharles S Zuker
Oct 17, 2002·The Journal of Physiology·Alejandro CaicedoStephen D Roper
Nov 5, 2002·Nature Reviews. Neuroscience·Gilles Laurent
Sep 11, 2003·Journal of Neurophysiology·Patricia M Di Lorenzo, Jonathan D Victor
Jun 24, 2004·Journal of Neurophysiology·Amir BaharEhud Ahissar
Aug 24, 2004·Current Opinion in Neurobiology·Kristin Scott
Dec 3, 2004·Journal of Neurophysiology·Alfredo Fontanini, Donald B Katz

❮ Previous
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Citations

Feb 2, 2020·Cellular and Molecular Life Sciences : CMLS·Ranier GutierrezSidney A Simon
Feb 29, 2020·Experimental Biology and Medicine·Stephanie M StaszkoMax L Fletcher
Mar 29, 2020·Sensors·Elena von MolitorTiziana Cesetti
Jun 24, 2020·Current Nutrition Reports·Glenn S Gerhard
Jul 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andrés Molero-Chamizo, Guadalupe Nathzidy Rivera-Urbina
Mar 18, 2020·Proceedings of the National Academy of Sciences of the United States of America·Emanuele PorcuToemme Noesselt
Oct 9, 2020·Pflügers Archiv : European journal of physiology·Elena von MolitorTiziana Cesetti
Jan 27, 2021·Current Biology : CB·Patricia M Di Lorenzo
May 1, 2021·International Journal of Molecular Sciences·Melania MelisIole Tomassini Barbarossa
Sep 24, 2019·Cell·Jin ZhangCharles S Zuker
Jul 10, 2021·Frontiers in Human Neuroscience·Elena von MolitorTiziana Cesetti
Nov 10, 2021·PLoS Computational Biology·Javier J HowSreekanth H Chalasani

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