journal cover

Recombinant BCG Tokyo (Ag85A) protects cynomolgus monkeys (Macaca fascicularis) infected with H37Rv Mycobacterium tuberculosis

Tuberculosis

Nov 1, 2007

Isamu SugawaraT Taniyama

Get paper from

Abstract

One tuberculosis vaccine candidate that has shown a promising degree of protective efficacy in guinea pigs is recombinant BCG Tokyo (Ag85A)(rBCG-Ag85A[Tokyo]). As a next step, cynomolgus monkeys were utilized because they are susceptible to Mycobacterium tuberculosis and develop a conti...read more

Mentioned in this Paper

Entire Spleen
Macaca
Platyrrhini
IL2 gene
Skin Structure of Back
Tuberculosis, Pulmonary
Monkeys
Old tuberculin
Coughing
Histopathological Aspects
Paper Details
References
  • References17
  • Citations20
12
  • References17
  • Citations20
12

Similar Papers Found In These Feeds

Tuberculosis

Tuberculosis is an infectious disease usually caused by Mycobacterium tuberculosis bacteria. Discover the latest research on tuberculosis here.

DNA Vaccine Delivery: Particulates

Bomaterial-based delivery systems based on micro- and nanoparticles that encapsulate plasmid DNA represent the most promising strategy for DNA vaccine delivery. Microparticulate delivery systems allow for passive targeting to antigen presenting cells through size exclusion and can allow for sustained presentation of DNA to cells through degradation and release of encapsulated vaccines. In contrast, nanoparticle encapsulation leads to increased internalization, overall greater transfection efficiency, and the ability to increase uptake across mucosal surfaces. Discover the latest research on DNA vaccine delivery here

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Immunomodulating Agents

Immunomodulating agents are substances that stimulate or suppresse the immune system and may help the body combat againsts cancer, infection, or other diseases. Discover the latest research on immunomodulating agents here.

Respiratory: Allergy, Immunology & Inflammation

This feed has been developed in conjunction with the American Thoracic Society for the benefit of its Allergy, Immunology, and Inflammation Assembly. It highlights new and impactful papers on allergy, asthma, genetics, and the pathogenesis of lung diseases.

© 2019 Meta ULC. All rights reserved

Recombinant BCG Tokyo (Ag85A) protects cynomolgus monkeys (Macaca fascicularis) infected with H37Rv Mycobacterium tuberculosis

Tuberculosis

Nov 1, 2007

Isamu SugawaraT Taniyama

PMID: 17720625

DOI: 10.1016/j.tube.2007.06.002

Abstract

One tuberculosis vaccine candidate that has shown a promising degree of protective efficacy in guinea pigs is recombinant BCG Tokyo (Ag85A)(rBCG-Ag85A[Tokyo]). As a next step, cynomolgus monkeys were utilized because they are susceptible to Mycobacterium tuberculosis and develop a conti...read more

Mentioned in this Paper

Entire Spleen
Macaca
Platyrrhini
IL2 gene
Skin Structure of Back

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References17
  • Citations20
12
  • References17
  • Citations20
12

Get paper from

/papers/recombinant-bcg-tokyo-ag85a-protects-cynomolgus/17720625