Get paper from

journal cover

Recombination impacts damaging and disease mutation accumulation in human populations

bioRxiv

Jun 8, 2014

Julie G HussinPhilip Awadalla

Get paper from

Abstract

MMany decades of theory have demonstrated that in non-recombining systems, slightly deleterious mutations accumulate non-reversibly1, potentially driving the extinction of many asexual species. Non-recombining chromosomes in sexual organisms are thought to have degenerated in a similar ...read more

Mentioned in this Paper

Biologic Degeneration
Crossing Over, Genetic
Mutation Abnormality
Genome
Abnormal Degeneration
Recombination, Genetic
Exons
Genome, Human
Genomics
Sequencing
14
1
52
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Recombination impacts damaging and disease mutation accumulation in human populations

    bioRxiv

    Jun 8, 2014

    Julie G HussinPhilip Awadalla

    PMID: 990006064

    DOI: 10.1101/006064

    Abstract

    MMany decades of theory have demonstrated that in non-recombining systems, slightly deleterious mutations accumulate non-reversibly1, potentially driving the extinction of many asexual species. Non-recombining chromosomes in sexual organisms are thought to have degenerated in a similar ...read more

    Mentioned in this Paper

    Biologic Degeneration
    Crossing Over, Genetic
    Mutation Abnormality
    Genome
    Abnormal Degeneration
    14
    1
    52

    Related Papers

    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/recombination-impacts-damaging-and-disease/990006064