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Recombination impacts damaging and disease mutation accumulation in human populations
bioRxiv
Jun 8, 2014
Julie G HussinPhilip Awadalla
PMID: 990006064
DOI: 10.1101/006064
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Abstract
MMany decades of theory have demonstrated that in non-recombining systems, slightly deleterious mutations accumulate non-reversibly1, potentially driving the extinction of many asexual species. Non-recombining chromosomes in sexual organisms are thought to have degenerated in a similar ...read more
Mentioned in this Paper
Biologic Degeneration
Crossing Over, Genetic
Mutation Abnormality
Genome
Abnormal Degeneration
Recombination, Genetic
Exons
Genome, Human
Genomics
Sequencing
14
1
52
Paper Details
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Recombination impacts damaging and disease mutation accumulation in human populations
Abstract
MMany decades of theory have demonstrated that in non-recombining systems, slightly deleterious mutations accumulate non-reversibly1, potentially driving the extinction of many asexual species. Non-recombining chromosomes in sexual organisms are thought to have degenerated in a similar ...read more
Mentioned in this Paper
Biologic Degeneration
Crossing Over, Genetic
Mutation Abnormality
Genome
Abnormal Degeneration
14
1
52
Paper Details
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- Citations
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We're still populating references for this paper, please check back later.
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