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Recombination rate and selection strength in HIV intra-patient evolution

PLoS Computational Biology

Jan 1, 2010

Richard A. Neher, Thomas Kenneth Leitner

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Abstract

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the parameters governing genetic diversification and the s...read more

Mentioned in this Paper

Immune System
Sampling - Surgical Action
Retroviridae
Dysequilibrium Syndrome
Genetic Linkage
Genetic Polymorphism
Mutation Abnormality
Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
Genome
Selection, Genetic
3
128
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Recombination rate and selection strength in HIV intra-patient evolution

PLoS Computational Biology

Jan 1, 2010

Richard A. Neher, Thomas Kenneth Leitner

PMID: 20126527

DOI: 10.1371/journal.pcbi.1000660

Abstract

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the parameters governing genetic diversification and the s...read more

Mentioned in this Paper

Immune System
Sampling - Surgical Action
Retroviridae
Dysequilibrium Syndrome
Genetic Linkage
3
128

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References40
  • Citations68
1234
  • References40
  • Citations68

Get paper from

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