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Recombination rates and genomic shuffling in human and chimpanzee--a new twist in the chromosomal speciation theory

Molecular Biology and Evolution

Dec 4, 2012

Marta FarréA Ruiz-Herrera

Abstract

A long-standing question in evolutionary biology concerns the effect of recombination in shaping the genomic architecture of organisms and, in particular, how this impacts the speciation process. Despite efforts employed in the last decade, the role of chromosomal reorganizations in the...read more

Mentioned in this Paper

Pongidae
Genome
Recombination, Genetic
Chromosome Breakpoint Sequence
Hominidae
Centromere
Chromosomes, Human
Pongo
Pan troglodytes
Genomics
13
4
88
Paper Details
References
  • References70
  • Citations22
12345...
  • References70
  • Citations22
123

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Recombination rates and genomic shuffling in human and chimpanzee--a new twist in the chromosomal speciation theory

Molecular Biology and Evolution

Dec 4, 2012

Marta FarréA Ruiz-Herrera

PMID: 23204393

DOI: 10.1093/molbev/mss272

Abstract

A long-standing question in evolutionary biology concerns the effect of recombination in shaping the genomic architecture of organisms and, in particular, how this impacts the speciation process. Despite efforts employed in the last decade, the role of chromosomal reorganizations in the...read more

Mentioned in this Paper

Pongidae
Genome
Recombination, Genetic
Chromosome Breakpoint Sequence
Hominidae
Centromere
Chromosomes, Human
Pongo
Pan troglodytes
Genomics
13
4
88

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Structure of Centromere Chromatin (Keystone)

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Centromere in DNA replication

Centromere identity must be maintained through multiple generations. A new study reveals a Constitutive Centromere-Associated Network (CCAN)-dependent retention of CENP-A, a key epigenetic mark for centromeres, in centromeres during DNA replication and a replication-dependent error correction to eliminate ectopic CENP-A in chromosome arms. Discover the latest research on centromere in DNA replication here.

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Paper Details
References
  • References70
  • Citations22
12345...
  • References70
  • Citations22
123
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