Recommandations sur l'utilisation du vaccin antirotavirus chez les nourrissons

Paediatrics & Child Health
Nicole Le Saux

Abstract

Le présent document de principes fournit de l'information sur l'infection à rotavirus clinique et les vaccins antirotavirus au Canada. Depuis l'adoption des programmes de vaccination antirotavirus financés par les gouvernements au Canada, les preuves s'accumulent quant à l'efficacité des vaccins antirotavirus pour prévenir la gastroentérite aiguë. Selon les données à jour, l'efficacité du vaccin serait de l'ordre de 85 % pour prévenir une maladie grave, y compris les hospitalisations et les consultations à l'urgence, lorsque la couverture vaccinale est élevée. De plus, une importante protection collective est attestée chez les enfants plus âgés. La surveillance postcommercialisation a permis de déceler une très légère augmentation du risque d'invagination chez les enfants (un à trois cas sur 100000), qui se manifeste généralement dans la semaine suivant la vaccination. Les nourrissons qui ont une immunodéficience marquée, démontrée ou présumée, ne devraient pas recevoir ce vaccin.

References

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