Recommendations for Institutions Transitioning to High-Sensitivity Troponin Testing: JACC Scientific Expert Panel.

Journal of the American College of Cardiology
James L JanuzziAllan S Jaffe

Abstract

High-sensitivity cardiac troponin (hs-cTn) I or T methods have been in use in certain regions for years but are now increasingly globally adopted, including in the United States. Accordingly, inevitable challenges are created for institutions transitioning from conventional cardiac troponin (cTn) assays. hs-cTn assays have higher analytic precision at lower concentrations, yielding greater clinical sensitivity for myocardial injury and allowing accurate recognition of small changes in troponin concentration (rise or fall) within a short time frame. Although much of the knowledge regarding troponin biology that was applicable with older troponin assays still holds true, considerable education regarding the differences between conventional cTn and hs-cTn is needed before medical systems convert to the newer methods. This includes a basic understanding of how hs-cTn testing differs from conventional cTn testing and how it is best deployed in different settings, such as the emergency department and inpatient services. This Expert Panel will review important concepts for institutional transition to hs-cTn methodology, providing recommendations useful for education before implementation.

Citations

Jul 11, 2019·Circulation. Heart Failure·L Kristin Newby
Jan 7, 2020·European Heart Journal·Adrian P BanningThomas F Lüscher
Jul 4, 2020·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Pierre Hausfater, Laetitia Velly
Sep 25, 2020·BMJ Evidence-based Medicine·Ali A AlsaadMahalakshmi Halasyamani
Aug 28, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nishant R ShahDavid E Winchester
Jun 20, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Michael C Kontos, Todd C Villines
Apr 2, 2020·Current Cardiology Reports·Michael C Kontos, Jeremy S Turlington
Oct 23, 2020·Clinical Cardiology·Enrico G FerroBenjamin M Scirica
Dec 10, 2020·Journal of Pharmaceutical and Biomedical Analysis·Maud SavonnetArnaud Buhot
Jan 21, 2021·The New England Journal of Medicine·Nandita S ScottR Neal Smith
Jan 22, 2021·Circulation Research·Matthew NayorRamachandran S Vasan
Feb 9, 2021·Clinical Chemistry and Laboratory Medicine : CCLM·Aldo ClericoMario Plebani
Mar 13, 2021·Journal of the American College of Cardiology·Inbar RaberJames L Januzzi
Oct 25, 2020·Biomedical Journal·Giuseppe Lippi, Fabian Sanchis-Gomar
Jun 26, 2021·Journal of the American College of Cardiology·Olatunde OlaYader Sandoval
Jun 26, 2021·Journal of the American College of Cardiology·Ishani GanguliJason H Wasfy
Jul 6, 2021·American Journal of Clinical Pathology·Leslie J DonatoBrad S Karon
Jul 6, 2021·Clinical Chemistry and Laboratory Medicine : CCLM·Aldo ClericoMario Plebani
Jan 6, 2021·Journal of Cardiovascular Medicine·Marco A PerroneAldo Clerico

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.