Recommended breast cancer surveillance guidelines. American Society of Clinical Oncology

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Abstract

To determine an effective, evidence-based postoperative surveillance strategy for the detection and treatment of recurrent breast cancer. Tests are recommended only if they have an impact on the outcomes specified by the American Society of Clinical Oncology (ASCO) for clinical practice guidelines. All tests described in the literature for postoperative monitoring were considered. In addition, the data were critically evaluated to determine the optimal frequency of monitoring. Outcomes of interest include overall and disease-free survival, quality of life, toxicity reduction, and secondarily cost-effectiveness. A search was performed to determine all relevant articles published over the past 20 years on the efficacy of surveillance testing for breast cancer recurrence. These publications comprised both retrospective and prospective studies. Levels of evidence and guideline grades were rated by a standard process. More weight was given to studies that tested a hypothesis that directly related testing to one of the primary outcomes in a randomized design. BENEFITS/HARMS/COSTS: The possible consequences of false-positive and negative tests were considered in evaluating a preference for one of two tests that provided similar inform...Continue Reading

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