Recommending analgesics for people with asthma

American Journal of Therapeutics
C Jenkins

Abstract

Asthma is a common condition, affecting approximately 7% of people worldwide. However, the prevalence varies among countries, and in Australia, asthma affects 10% of adults and approximately 20% of children. For some of these patients, ingredients in some over-the-counter analgesics may pose problems. Aspirin sensitivity, defined as urticaria, angioedema, or rhinitis after aspirin ingestion, affects only 0.3% of the general population. However, certain patient groups, such as asthmatics, are at an increased risk, with reports of an incidence as high as 20% in this patient population. This phenomenon is not restricted to aspirin, as all nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit the enzyme cyclooxygenase display a high incidence of cross-sensitivity. In contrast, paracetamol (acetaminophen) is well tolerated by the majority of people with asthma and is seldom associated with cross-sensitivity. Determining who is likely to be affected is difficult because the sequence of symptoms is hard to predict, and patients often do not associate an asthma attack with the use of aspirin or an NSAID. The only definitive way to diagnose sensitivity is by provocation tests. In view of these difficulties, it is important for heal...Continue Reading

Citations

Jan 22, 2005·American Journal of Therapeutics·Garry G Graham, Kieran F Scott
Jan 22, 2005·American Journal of Therapeutics·C Jane NiklesDavid Wilkinson
Aug 25, 2007·The Journal of Allergy and Clinical Immunology·Marcus ShakerMark S Dykewicz
Jul 8, 2011·The International Journal of Pharmacy Practice·Rodney StosicIan Adams
Dec 6, 2006·The Laryngoscope·Tatu KemppainenJuhani Nuutinen
Jun 19, 2007·The Laryngoscope·Tatu P KemppainenJuhani Nuutinen
Mar 1, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Garry G GrahamRichard O Day
Jan 9, 2003·Expert Opinion on Pharmacotherapy·Gül Karakaya, A Fuat Kalyoncu
Jun 18, 2005·Anaesthesia and Intensive Care·G M Palmer
Apr 10, 2002·American Journal of Therapeutics·Alison Jones

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.