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Reconstructing subclonal composition and evolution from whole genome sequencing of tumors

bioRxiv

Jun 27, 2014

Amit G DeshwarQuaid Morris

Abstract

Tumors often contain multiple, genetically distinct subpopulations of cancerous cells. These so-called subclonal populations are defined by distinct somatic mutations that include point mutations such as single nucleotide variants and small indels - collectively called simple somatic mu...read more

Mentioned in this Paper

DNA Resequencing
Sequencing
Chronic Lymphocytic Leukemia
Subclone
Neoplasms
Nucleotides
Tumor Cells, Malignant
Superficial Spreading Malignant Melanoma of Skin
DNA Copy Number Variations
CNV Protocol
13
4
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Reconstructing subclonal composition and evolution from whole genome sequencing of tumors

bioRxiv

Jun 27, 2014

Amit G DeshwarQuaid Morris

PMID: 990006692

DOI: 10.1101/006692

Abstract

Tumors often contain multiple, genetically distinct subpopulations of cancerous cells. These so-called subclonal populations are defined by distinct somatic mutations that include point mutations such as single nucleotide variants and small indels - collectively called simple somatic mu...read more

Mentioned in this Paper

DNA Resequencing
Sequencing
Chronic Lymphocytic Leukemia
Subclone
Neoplasms
Nucleotides
Tumor Cells, Malignant
Superficial Spreading Malignant Melanoma of Skin
DNA Copy Number Variations
CNV Protocol
13
4

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