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Reconstructing subclonal composition and evolution from whole genome sequencing of tumors

bioRxiv

Jun 27, 2014

Amit G. DeshwarQuaid D. Morris

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Abstract

Tumors often contain multiple, genetically distinct subpopulations of cancerous cells. These so-called subclonal populations are defined by distinct somatic mutations that include point mutations such as single nucleotide variants and small indels ? collectively called simple somatic mu...read more

Mentioned in this Paper

Tumor Cells, Malignant
Chronic Lymphocytic Leukemia
DNA Copy Number Variations
Genome Sequencing
Whole Genome Sequencing
Population Group
Contingent Negative Variation
Point Mutation
Structure
CNV Protocol
13
4
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  • Reconstructing subclonal composition and evolution from whole genome sequencing of tumors

    bioRxiv

    Jun 27, 2014

    Amit G. DeshwarQuaid D. Morris

    PMID: 990006692

    DOI: 10.1101/006692

    Abstract

    Tumors often contain multiple, genetically distinct subpopulations of cancerous cells. These so-called subclonal populations are defined by distinct somatic mutations that include point mutations such as single nucleotide variants and small indels ? collectively called simple somatic mu...read more

    Mentioned in this Paper

    Tumor Cells, Malignant
    Chronic Lymphocytic Leukemia
    DNA Copy Number Variations
    Genome Sequencing
    Whole Genome Sequencing
    13
    4

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