Reconstruction of loads in the fibrosa and ventricularis of porcine aortic valves

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
I Vesely

Abstract

The main structural components of aortic valve cusps, the fibrosa and ventricularis, are pre loaded by virtue of their attachment to each other. The fibrosa is under compression and the ventricularis is under tension. Once separated from each other, these internal stresses are relieved, and the fibrosa elongates and the ventricularis shrinks. It then becomes impossible to determine what fraction of the load is carried by the two layers at a given strain, using the standard superposition of tension vs strain curves. To enable the superposition approach, we needed to adjust the tension/ strain curves of the fibrosa and ventricularis, and duplicate the pre load that exists in these layers. We, therefore, iteratively shifted these curves and compared their arithmetic sum to the tension curve for the whole intact cusp, using a sum-of-squares error function. The best fits occurred when the fibrosa and ventricularis were shifted to the right and left by amounts corresponding to a true strain of epsilon = 0.26 and 0.10 for the fibrosa and ventricularis in the radial directions. In the circumferential direction, the best fit was achieved for shifts of epsilon = -0.11 and 0.010 for the fibrosa and ventricularis, respectively. This 26% co...Continue Reading

Citations

May 21, 1998·Journal of Biomechanics·I Vesely
Jun 12, 2010·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Elizabeth H StephensK Jane Grande-Allen
Dec 3, 2013·Biomechanics and Modeling in Mechanobiology·Rachel M Buchanan, Michael S Sacks
Sep 13, 2003·Journal of Biomechanical Engineering·Niels J DriessenFrank P Baaijens
Aug 3, 2005·Journal of Biomechanical Engineering·Niels J B DriessenFrank P T Baaijens
Sep 25, 2007·Journal of Biomechanical Engineering·John A Stella, Michael S Sacks
Feb 26, 2011·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Elizabeth H StephensK Jane Grande-Allen
Feb 4, 2009·Journal of Biomedical Materials Research. Part a·Elizabeth H StephensK Jane Grande-Allen
Mar 15, 2006·Journal of Biomechanics·Niels J B DriessenFrank P T Baaijens
Sep 17, 2013·Journal of the Mechanical Behavior of Biomedical Materials·A L F SoaresF P T Baaijens
Oct 15, 2005·Circulation Research·Ivan Vesely
Nov 21, 2007·Cardiovascular Engineering·Eli J Weinberg, Mohammad Reza Kaazempur Mofrad

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