Reconstruction of right ventricular outflow tract in neonates and infants using valved cryopreserved femoral vein homografts

The Journal of Thoracic and Cardiovascular Surgery
Ofer SchillerR A Jonas

Abstract

Aortic or pulmonary homografts (A/PHs) are common biomaterials used for restoration of right ventricle to pulmonary artery continuity for repair of various congenital heart defects. The smaller sized homografts required for early primary repair in neonates and infants are prone to early failure and are in short supply. Due to these limitations, since 2008 it has been our preference to use valved segments of cryopreserved femoral vein homograft (cFVH) for right ventricle to pulmonary artery reconstruction. This study was undertaken to assess the performance of cFVH compared with A/PH in neonates and infants. A retrospective review of all infants and neonates who underwent biventricular early primary repair with right ventricle to pulmonary artery reconstruction using homograft conduits at a single center was conducted. Patients who received cFVH constituted the study group, whereas all other patients received A/PH and formed the control group. Patients with pulmonary atresia, ventricular septal defect, and major aortopulmonary collaterals who had conduits placed to promote pulmonary artery growth or to unifocalized pulmonary vasculature were excluded from the study because they have different clinical indications for reoperation...Continue Reading

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Citations

Aug 15, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Anthony AzakieRichard W Bianco
Aug 30, 2017·Cardiology in the Young·Mario Briceno-MedinaChristopher J Knott-Craig
Jun 18, 2019·The Journal of Thoracic and Cardiovascular Surgery·T K Susheel KumarChristopher J Knott-Craig

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