Reconstruction with biological methods following intercalary excision of femoral diaphyseal tumors

Journal of Orthopaedic Surgery
Abhijeet Ashok SalunkeMayur Kamani

Abstract

The aim of this study was to assess outcomes of biological (nonvascularized fibula grafts and extracorporeal irradiated autologous bone grafts) methods used for reconstruction of intercalary defects after resection of femoral diaphyseal tumors. This study included 28 patients who had undergone intercalary resection in femoral diaphyseal tumors between 2011 and 2016. The mean follow-up period was 24 months (range 12-57 months). The mean union time for diaphyseo-diaphyseal union was 10.5 and 11 months in nonvascularized fibula group and extracorporeal radiotherapy (ECRT) group, respectively. The mean union time for metaphyseo-diaphyseal union was 6.5 months in both nonvascularized fibula and ECRT groups. Six patients had distant metastasis, and one patient had local recurrence. The mean Musculoskeletal Tumor Society score was 28 at the last follow-up. Two patients had surgical site infection in the nonvascularized fibula group. Implant failure was found in one patient of the ECRT group requiring revision surgery. Three patients had nonunion (two from the nonvascularized fibula group and one from the ECRT group). The present study indicates that the biological reconstruction modalities provide good functional outcomes in diaphysea...Continue Reading

References

Jan 1, 1989·International Orthopaedics·R CapannaM Campanacci
Jan 1, 1995·The Journal of Bone and Joint Surgery. American Volume·B A AlmanJ I Krajbich
Feb 1, 1994·Acta Orthopaedica Scandinavica·J A CaraJ Cañadell
Jan 1, 1997·The Journal of Bone and Joint Surgery. American Volume·E Ortiz-CruzH J Mankin
Jan 1, 1997·The Journal of Bone and Joint Surgery. British Volume·R W HsuE Y Chao
Aug 16, 2000·Clinical Orthopaedics and Related Research·D DonatiM Mercuri
Oct 13, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·G BacciM DePaolis
Mar 7, 2002·Archives of Orthopaedic and Trauma Surgery·D DonatiG Bacci
Feb 6, 2004·Journal of Surgical Oncology·Craig H GerrandJay S Wunder
May 1, 2004·The Journal of Bone and Joint Surgery. American Volume·Edmund Y S ChaoFranklin H Sim
Sep 4, 2004·Clinical Orthopaedics and Related Research·D Luis MuscoloEduardo Abalo
Jan 6, 2005·International Orthopaedics·E AldlyamiR M Tillman
Mar 2, 2005·Journal of Reconstructive Microsurgery·Rob PollockDavid Pennington
Oct 6, 2005·Clinical Orthopaedics and Related Research·R L M DeijkersA H M Taminiau
Dec 21, 2005·The Journal of Bone and Joint Surgery. British Volume·L E RamseierG U Exner
Nov 1, 2006·The Journal of Bone and Joint Surgery. British Volume·E R Ahlmann, L R Menendez
Dec 13, 2006·The Journal of Bone and Joint Surgery. British Volume·S ShalabyA Bassiony
Feb 27, 2007·The Journal of Bone and Joint Surgery. British Volume·A H Krieg, F Hefti
Jan 15, 2008·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B FuchsF H Sim
Aug 8, 2009·Clinical Orthopaedics and Related Research·Melissa N ZimelErnest U Conrad
Feb 11, 2010·Clinical Orthopaedics and Related Research·Benjamin J Miller, Walter W Virkus
Jun 2, 2010·The Journal of Bone and Joint Surgery. British Volume·S A HannaT W R Briggs
Jul 20, 2011·The Journal of Bone and Joint Surgery. British Volume·M D SewellT W R Briggs
Nov 8, 2011·Orthopaedics & Traumatology, Surgery & Research : OTSR·T van IsackerC Delloye
Mar 3, 2012·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Kazuhiro TanakaFuminori Kanaya
Jul 20, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P X TanJ N Shen
Aug 9, 2013·Strategies in Trauma and Limb Reconstruction·Zile Singh KunduSukhbir Singh Sangwan

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
amputation

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.