Recovery of Dementia Syndrome following Treatment of Brain Inflammation

Dementia and Geriatric Cognitive Disorders Extra
Jong-Hoon LeeSang-Suk Oh

Abstract

This research aims to prevent progression from mild cognitive impairment (MCI) to Alzheimer's disease. A Japanese study of leprosy patients revealed that the incidence of dementia in leprosy patients was lower than that in patients taking dapsone who had never been treated. But a similar study the following year refuted the finding of less dementia in leprosy patients taking dapsone. According to conflicting reports, Mycobacterium leprae was a factor in reducing the incidence of Alzheimer's disease. Thus, we formed a hypothesis that if dapsone is administered to patients without leprosy but with MCI and the prophylactic effect of dementia syndrome is observed over a long period of time, we can determine whether dapsone can prevent the progression of MCI to dementia syndrome. If dementia does not occur after treating inflammation in brain cells while dementia develops after a certain long-term period (usually within 2-3 years), brain cell inflammation can be demonstrated as the cause of dementia. This is a prospective cohort research. We report on an elderly patient diagnosed with MCI from February 2008 to January 2019. The patient took dapsone 100 mg once a day from 2010 to 2015 for the treatment of MCI. Since 2016, the product...Continue Reading

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Citations

Aug 23, 2020·International Journal of Molecular Sciences·Jong-Hoon LeeSangsuk Oh
Jul 3, 2021·Vaccines·Badar KanwarJong-Hoon Lee
Jul 13, 2021·Dementia and Geriatric Cognitive Disorders Extra·Jong-Hoon LeeSu-Hee Choi
Jul 13, 2021·Dementia and Geriatric Cognitive Disorders Extra·Asif KhattakSu-Hee Choi

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