PMID: 7034240Dec 1, 1981Paper

Recovery of Paracoccidioides brasiliensis from a partially calcified lymph node lesion by microaerophilic incubation of liquid media

Sabouraudia
A RestrepoV Bedoya

Abstract

Surgical specimens were obtained from a patient who had had life-threatening paracoccidioidomycosis 5 years previously. Residual lesions were found in the mesenteric lymph nodes; there were areas of caseous necrosis separated from the surrounding tissue by a fibrous capsule made of connective tissue. Abundant P. brasiliensis cells, many of which appeared degenerated, were observed in the necrotic material. Primary isolation was possible only under the microaerophilic conditions offered by fluid media kept stationary at 36 degrees C. Cultures in solid media were obtained after serial passages and gradual accommodation of the strain to aerobic incubation. It is apparent that P. brasiliensis yeast cells can become accustomed to reduced oxygen tension in the tissues. In this way, they are able to withstand the passing of time without completely losing their viability.

References

Jul 1, 1978·The American Journal of Tropical Medicine and Hygiene·D A StevensI Gómez
Aug 1, 1980·Journal of Clinical Microbiology·A Restrepo, B E Jiménez
Jul 1, 1980·Antimicrobial Agents and Chemotherapy·A Restrepo, M D Arango

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Citations

Apr 1, 1987·Revista Da Sociedade Brasileira De Medicina Tropical·M FrancoN G Mota
Mar 30, 2005·Expert Opinion on Pharmacotherapy·Maria Aparecida Shikanai Yasuda
Apr 26, 2005·The Journal of Biological Chemistry·Maria Sueli S FelipeUNKNOWN PbGenome Network
Feb 1, 1987·Journal of Medical and Veterinary Mycology : Bi-monthly Publication of the International Society for Human and Animal Mycology·M Franco
May 1, 1989·Revista Do Instituto De Medicina Tropical De São Paulo·M FrancoM Miyaji
Apr 1, 1993·Clinical Microbiology Reviews·E BrummerA Restrepo

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