Recovery of supraspinal control of leg movement in a chronic complete flaccid paraplegic man after continuous low-frequency pelvic nerve stimulation and FES-assisted training

Spinal Cord Series and Cases
Marc Possover, Axel Forman

Abstract

More than 30 years ago, functional electrical stimulation (FES) was developed as an orthotic system to be used for rehabilitation for SCI patients. In the present case report, FES-assisted training was combined with continuous low-frequency stimulation of the pelvic somatic nerves in a SCI patient. We report on unexpected findings in a 41-year-old man with chronic complete flaccid paraplegia, since he was 18 years old, who underwent spinal stem cell therapy and a laparoscopic implantation of neuroprosthesis (LION procedure) in the pelvic lumbosacral nerves. The patient had complete flaccid sensomotoric paraplegia T12 as a result of a motor vehicle accident in 1998. In June 2011, he underwent a laparoscopic implantation of stimulation electrodes to the sciatic and femoral nerves for continuous low-frequency electrical stimulation and functional electrical stimulation of the pelvic nerves. Neither intraoperative direct stimulation of the pelvic nerves nor postoperative stimulation induced any sensation or muscle reactions. After 2 years of passive continuous low-frequency stimulation, the patient developed progressive recovery of electrically assisted voluntary motor functions below the lesions: he was first able to extend the ri...Continue Reading

References

Mar 31, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C D McCaigR Stewart
Dec 21, 2006·Spinal Cord·J D SteevesUNKNOWN International Campaign for Cures of Spinal Cord Injury Paralysis
Jul 30, 2008·Neurorehabilitation and Neural Repair·Ming-Chin LuYueh-Sheng Chen
Jun 2, 2012·Science·Rubia van den BrandGrégoire Courtine
Apr 16, 2013·Biochimica Et Biophysica Acta·Yu-Jung ChangLinyi Chen
Nov 26, 2013·Archives of Physical Medicine and Rehabilitation·Marc Possover

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