PMID: 8953420Nov 1, 1996Paper

Recovery of the hematopoietic system by Si-Jun-Zi-Tang in whole body irradiated mice

Journal of Ethnopharmacology
H Y HsuC C Lin

Abstract

The herbal formulation Si-Jun-Zi-Tang reduced the decrease of leukocytes, erythrocytes, thrombocytes and hematocrit in irradiated mice. In general, its protection was more effective in leukocytes and thrombocytes than other hematocytes. Protection of bone marrow stem cells by Si-Jun-Zi-Tang was markedly enhanced by increased radiotolerance under the dose ranging from 0 to 5 Gy. This increased radiotolerance led to a prolonged shoulder in the survival curve but did not influence the D0 value. Si-Jun-Zi-Tang exerted a beneficial effect on clinical syndromes such as anemia. From the results in this study, we concluded preliminarily that the most effective concentration with least toxicity was about 20 mg/20 g body weight. At this dose, levels of leukocytes as well as thrombocytes were enhanced significantly after chi-irradiation. Elevation of erythrocytes and hematocrits could also be found but was not significant.

References

Jan 1, 1991·The American Journal of Chinese Medicine·H Y HsuC C Lin
Jan 1, 1991·Annual Review of Immunology·M A Moore
Jun 1, 1988·The British Journal of Radiology·G L FloersheimA Bieri
Jan 1, 1993·The American Journal of Chinese Medicine·H Y HsuC C Lin

❮ Previous
Next ❯

Citations

May 30, 2002·Biological & Pharmaceutical Bulletin·Mehmet KocSeyithan Taysi
Apr 7, 2011·Biological & Pharmaceutical Bulletin·Alena Rajnochová SvobodováJitka Vostálová
Mar 31, 2005·Phytotherapy Research : PTR·Rajesh AroraRakesh Kumar Sharma
Jun 16, 2005·Mutagenesis·Tung-Kwang LeeLarry J Dobbs
Apr 25, 2019·BMC Complementary and Alternative Medicine·Jin-Yong ZhouShen-Lin Liu
Oct 20, 2020·Frontiers in Pharmacology·Anzheng NieChunsheng Zhu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.