Recreational and occupational physical activities and risk of breast cancer

Journal of the National Cancer Institute
M D GammonJ A Britton

Abstract

Physical activity has been hypothesized to reduce breast cancer risk, but an inverse association has not been consistently reported. In this review, we critically evaluate for coherence, validity, and bias the epidemiologic studies on recreational or occupational physical activity, discuss the biologic plausibility of the association, and identify areas for future research. Results from seven of nine studies suggest that higher levels of occupational physical activity may be associated with a reduction in risk, at least among a subgroup of women. Eleven of 16 investigations on recreational exercise reported a 12%-60% decrease in risk among premenopausal and postmenopausal women, although a dose-response trend was not evident in most of the studies. The reduction in risk associated with exercise was more likely to be observed in case-control studies than in cohort studies. Most investigations incompletely assessed physical activity, which contributed to conflicting findings on the optimal time period, duration, frequency, or intensity of activity to minimize risk. Physical activity may exert its effects through changes in menstrual characteristics, reduced body size, or alterations in immune function. In summary, most epidemiolo...Continue Reading

References

Sep 1, 1979·European Journal of Applied Physiology and Occupational Physiology·A BonenA N Belcastro
Jan 15, 1992·American Journal of Epidemiology·L BernsteinB E Henderson
Nov 1, 1992·Medicine and Science in Sports and Exercise·B Sternfeld
Jan 11, 1992·Advances in Experimental Medicine and Biology·R S PaffenbargerA L Wing
Oct 1, 1991·Medicine and Science in Sports and Exercise·J MoisanS Gingras
Sep 1, 1990·Epidemiology·F MeyerC Bouchard
Dec 1, 1990·International Journal of Sports Medicine·R J Shephard
May 1, 1990·Journal of Applied Physiology·A BroocksD Jeschke
Feb 1, 1989·The Journal of Clinical Endocrinology and Metabolism·A B LoucksS S Yen
Jun 1, 1989·American Journal of Epidemiology·J A CauleyJ G Powell
Jun 1, 1989·American Journal of Public Health·D AlbanesP R Taylor
Jan 1, 1988·Psychoneuroendocrinology·O G Cameron, R M Nesse
Oct 1, 1988·Sports Medicine·H W KohlS N Blair
Oct 15, 1988·Cancer·L Garfinkel, S D Stellman
Jan 1, 1988·European Journal of Cancer & Clinical Oncology·T J Key, M C Pike
May 1, 1988·The Journal of Clinical Endocrinology and Metabolism·M E NelsonW J Evans
Jan 1, 1987·The American Journal of Clinical Nutrition·P K Siiteri
Jun 1, 1986·The Journal of Clinical Endocrinology and Metabolism·E C FisherW J Evans
May 1, 1986·American Journal of Obstetrics and Gynecology·P T Ellison, C Lager
Jan 1, 1987·The American Journal of Clinical Nutrition·R S PaffenbargerA L Wing
Jan 1, 1987·The American Journal of Clinical Nutrition·J E VenaM K Swanson
Jan 1, 1987·The American Journal of Clinical Nutrition·R E FrischM Marguglio
Apr 1, 1985·The Journal of Clinical Endocrinology and Metabolism·D C CummingM R Fluker
Sep 1, 1985·Cancer·B E HendersonM C Pike
Jul 1, 1983·The Journal of Clinical Endocrinology and Metabolism·D Apter, R Vihko
Dec 1, 1984·The Journal of Clinical Endocrinology and Metabolism·A B Loucks, S M Horvath
Jun 1, 1984·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·B A BullenJ W McArthur
Mar 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A BonenA A Simpson
May 1, 1983·Fertility and Sterility·T W BoydenJ H Wilmore
Oct 2, 1981·JAMA : the Journal of the American Medical Association·R E FrischH Hermann
Jul 3, 1980·The New England Journal of Medicine·R E FrischL Vincent
Jul 1, 1995·Cancer Causes & Control : CCC·R MittendorfW C Willett
May 1, 1995·Epidemiology·C M Friedenreich, T E Rohan
Feb 1, 1995·Journal of the National Cancer Institute·P G TonioloB S Pasternack
Feb 1, 1995·Japanese Journal of Cancer Research : Gann·K HiroseS Tokudome
Mar 1, 1995·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·R J Shephard, P N Shek
Apr 1, 1995·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·C M Friedenreich, T E Rohan
Sep 1, 1994·International Journal of Sport Nutrition·M M Kanter

❮ Previous
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Citations

Dec 3, 2005·Breast Cancer Research and Treatment·Amy J MertensAaron R Folsom
Jan 20, 2010·Cancer Causes & Control : CCC·Angélica Angeles-LlerenasGabriela Torres-Mejía
Jul 31, 2012·Irish Journal of Medical Science·N M CumminsP Carroll
Jun 11, 1999·Journal of the American Dietetic Association·S G Affenito, J Kerstetter
Jun 6, 2003·Cancer Detection and Prevention·Joanna Kruk, Hassan Y Aboul-Enein
Apr 20, 2001·Maturitas·B S Hulka, P G Moorman
Oct 3, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F LeviC La Vecchia
May 3, 2003·Breast Cancer Research and Treatment·Mona OkashaGeorge Davey Smith
May 25, 2002·Acta Physiologica Scandinavica·K C WesterlindR Strange
Sep 22, 2000·Research Quarterly for Exercise and Sport·W J BrownA Bauman
Dec 2, 2008·Journal of Psychosocial Oncology·Suzanne C O'NeillMarc D Schwartz
Jan 11, 2003·American Journal of Epidemiology·Karen SteindorfJenny Chang-Claude
Aug 13, 1998·Journal of the National Cancer Institute·J F Dorgan
Aug 13, 1998·Journal of the National Cancer Institute·B RockhillG A Colditz
Jan 6, 2000·Journal of the National Cancer Institute·M M LeeD Eisenberg
Aug 21, 2004·Breast Cancer Research : BCR·Susan E HankinsonWalter C Willett
Oct 28, 2008·Annals of Surgical Oncology·Jennifer A LigibelEric P Winer
Oct 25, 2006·Proceedings of the National Academy of Sciences of the United States of America·Yao-Ping LuAllan H Conney
Aug 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·Yao-Ping LuAllan H Conney
Jul 12, 2014·Health Promotion International·Ian M LahartAmtul R Carmichael
Jul 13, 2002·International Journal of Cancer. Journal International Du Cancer·Tahereh MoradiPaul Lichtenstein
Nov 21, 2007·Seminars in Oncology Nursing·Antronette K Yancey, A Janet Tomiyama
Feb 14, 2007·Cancer Detection and Prevention·Joanna Kruk
Nov 23, 2006·Medical Hypotheses·Manuela Gago-DominguezJ Esteban Castelao
Oct 10, 2015·Cancer Causes & Control : CCC·Christine C EkengaDale P Sandler
Jan 24, 2007·American Journal of Industrial Medicine·Beata PeplonskaAaron Blair
Jun 23, 2006·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Beverly S Reigle
Jun 28, 2006·Australian and New Zealand Journal of Public Health·Lin Fritschi, Tim Driscoll
Sep 10, 2005·International Journal of Cancer. Journal International Du Cancer·Cheryl VigenAnna H Wu
May 27, 2005·Preventive Medicine·Celia Patricia KaplanSteven E Gregorich
Mar 6, 2004·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Michelle D Holmes, Candyce H Kroenke
Nov 9, 2004·Preventive Medicine·Marian L FitzgibbonAlan Dyer
Jun 14, 2012·Journal of Biomedical Informatics·Farzaneh TatariAhmad Sabahi
Nov 15, 2014·Journal of American College Health : J of ACH·Jennifer K BernatGlenn G Sparks
Jan 20, 2000·Journal of the National Cancer Institute·J VerloopF E van Leeuwen
Sep 10, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer A Ligibel
Feb 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jennifer A LigibelEric P Winer
Mar 8, 2000·Cancer·C R Baquet, P Commiskey
Jan 13, 2018·Annual Review of Public Health·Robert A Hiatt, Julia Green Brody
Apr 13, 2004·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Y T LagerrosC-C Hsieh
Jun 13, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·B A Stoll

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