Recruiting London gay men into an HIV vaccine trial: is it feasible?

AIDS Care
L SherrJ Elford

Abstract

This paper describes a study among HIV-negative gay men in London to examine willingness to volunteer for an HIV vaccine trial. HIV-negative gay men (n=506) were surveyed in central London gyms in February-March 2002. Information was collected on willingness to volunteer for an HIV vaccine trial, attitudes toward HIV vaccines and sexual risk behaviour. Men reporting unprotected anal intercourse (UAI) in the previous three months with a man of unknown or discordant HIV status were classified as being at high risk of exposure to HIV (n=94, 18.6%). The remainder, who reported no UAI or UAI only with another HIV-negative man, were considered to be at low risk (n=412, 81.4%). Just under a quarter of the HIV-negative men in the study (23.4%) said they were either quite likely or very likely to volunteer for an HIV vaccine trial. High-risk men were more likely to say they would volunteer for a trial than low-risk men (37.2% versus 20.2%, p<0.001). Of the 506 HIV-negative men surveyed, eight (1.6%) were both high risk and very likely to volunteer for an HIV vaccine trial, while a further 27 (5.3%) were both high risk and quite likely to volunteer. Based on these figures, we estimated that to recruit 1,000 high-risk HIV-negative men int...Continue Reading

References

Oct 1, 1986·Accident; Analysis and Prevention·G Blomquist
May 1, 1997·Accident; Analysis and Prevention·B Dulisse
May 1, 1997·Accident; Analysis and Prevention·F SagbergI A Saetermo
May 23, 1998·Accident; Analysis and Prevention·T S Dee
Jul 17, 1998·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·G J Wilde
Jul 17, 1998·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·B O'Neill, A Williams
Feb 12, 1999·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·R B Hays, S M Kegeles
Feb 12, 1999·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·S ScheerS Buchbinder
Jul 27, 1999·Journal of Acquired Immune Deficiency Syndromes : JAIDS·K M MacQueenT D Mastro
Aug 24, 1999·Journal of Acquired Immune Deficiency Syndromes : JAIDS·M O Johnson
Aug 5, 2000·International Journal of STD & AIDS·A Liau, G D Zimet
Jan 5, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·A R PérisséL H Harrison
Jan 6, 2001·Sexually Transmitted Infections·R A JenkinsS Nitayaphan
Mar 10, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·J W McGrathE Mugisha
Jul 27, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·J W McGrathE Mugisha
Jan 26, 2002·BMJ : British Medical Journal·Roy D MugerwaUNKNOWN HIV-1 Vaccine Trial Group
Apr 19, 2002·The Journal of Medicine and Philosophy·Keymanthri Moodley
May 2, 2002·Vaccine·Peter N Mugyenyi
May 11, 2002·Nature Reviews. Immunology·Harriet L Robinson
Dec 11, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jacqueline M O'ConnellRobert Remis
Dec 19, 2002·AIDS Research and Human Retroviruses·Paul Van De VenDean Murphy
Nov 26, 2003·The American Journal of Bioethics : AJOB·Elysa Koppelman

❮ Previous
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Citations

May 26, 2007·Sexual Health·Scott D Rhodes, Leland J Yee
Jun 2, 2009·The International Journal on Drug Policy·Lisa MaherLen Liao
Feb 12, 2009·Tropical Medicine & International Health : TM & IH·Eugene RuzagiraAnatoli Kamali
Sep 3, 2004·BMC Public Health·Jonathan ElfordGraham Hart

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