Recruitment methods and costs for a randomized, placebo-controlled trial of chiropractic care for lumbar spinal stenosis: a single-site pilot study

Journal of Manipulative and Physiological Therapeutics
J A CambronGregory D Cramer

Abstract

The purpose of this article is to describe the methods for recruitment in a clinical trial on chiropractic care for lumbar spinal stenosis. This randomized, placebo-controlled pilot study investigated the efficacy of different amounts of total treatment dosage over 6 weeks in 60 volunteer subjects with lumbar spinal stenosis. Subjects were recruited for this study through several media venues, focusing on successful and cost-effective strategies. Included in our efforts were radio advertising, newspaper advertising, direct mail, and various other low-cost initiatives. Of the 1211 telephone screens, 60 responders (5.0%) were randomized into the study. The most successful recruitment method was radio advertising, generating more than 64% of the calls (776 subjects). Newspaper and magazine advertising generated approximately 9% of all calls (108 subjects), and direct mail generated less than 7% (79 subjects). The total direct cost for recruitment was $40 740 or $679 per randomized patient. The costs per randomization were highest for direct mail ($995 per randomization) and lowest for newspaper/magazine advertising ($558 per randomization). Success of recruitment methods may vary based on target population and location. Planning o...Continue Reading

References

Feb 24, 2001·Journal of Manipulative and Physiological Therapeutics·J A Cambron
Mar 14, 2002·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Cheryl HawkRoni Evans
Jan 23, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Pamela F RodeheaverDebra E Lyon
Jun 15, 2004·Journal of Manipulative and Physiological Therapeutics·Jerrilyn A CambronCynthia R Long
Jul 21, 2004·BMC Complementary and Alternative Medicine·Karen J ShermanDavid M Eisenberg
Dec 13, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Maruti Ram GudavalliAvinash G Patwardhan
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Apr 29, 2009·The Spine Journal : Official Journal of the North American Spine Society·Leonid KalichmanDavid J Hunter

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Citations

Jun 9, 2012·Clinical Nurse Specialist CNS·Ukamaka M OrucheKristen Mullins
Nov 29, 2013·British Journal of Clinical Pharmacology·Adrian HapcaIsla S Mackenzie
Aug 12, 2014·Journal of Manipulative and Physiological Therapeutics·Jerrilyn A CambronGregory D Cramer
Jul 28, 2009·Complementary Therapies in Medicine·Lisa M Pastore, Parchayi Dalal
Sep 25, 2020·Journal of Medical Internet Research·Kelli L AhmedRobin P Goin-Kochel
Mar 8, 2017·Journal of Manipulative and Physiological Therapeutics·Gregory D CramerKim Ross

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