PMID: 8951510Jan 1, 1996Paper

Rectal cancer recurrence after prior resection and radiotherapy: palliation following additional surgery

International Journal of Colorectal Disease
J F VerreesPaul H Sugarbaker

Abstract

Patients with rectal cancer may develop local recurrence despite cancer resection plus treatment with high dose radiation therapy. In this report, symptomatic patients received benefit from repeat resection. The morbidity and mortality can be maintained at an acceptable level with meticulous dissections and consistent use of reconstructive procedures. The primary treatment of rectal carcinoma is surgical excision to remove the primary tumor and its draining lymphatic systems. Postoperative radiotherapy may be recommended if tumor has penetrated through the full thickness of the bowel wall, and where there is lymph node involvement. Despite such treatments, tumor may recur locally, producing symptoms relieved by palliative surgery. Between 1989 and 1995, twenty patients underwent 21 reoperations for locally recurrent rectal cancer. All patients previously had not only surgical resection but also radiotherapy as treatment. The clinical data available on these patients was critically evaluated. Eighty-nine dissections (4.5 per patient) and 39 reconstructive procedures (2.0 per patient) were required on these 20 patients to re-resect rectal cancer in an irradiated site. Major complications occurred in 4 of 21 reoperative procedures...Continue Reading

Citations

Jan 22, 2010·European Journal of Orthodontics·Tatiana dos Santos Ciccone de FariaCláudia Maria de Felício
Mar 5, 2013·Surgical Oncology Clinics of North America·Paul H Sugarbaker
Oct 23, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O ReerinkG A P Hospers
May 6, 1998·American Journal of Surgery·M Huguier, S Houry
Jan 5, 2016·The Cochrane Database of Systematic Reviews·Sarah E CousinsDavid J Feuer

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