Rectal fecal impaction treatment in childhood constipation: enemas versus high doses oral PEG

Pediatrics
Noor-L-Houda BekkaliMarc A Benninga

Abstract

We hypothesized that enemas and polyethylene glycol (PEG) would be equally effective in treating rectal fecal impaction (RFI) but enemas would be less well tolerated and colonic transit time (CTT) would improve during disimpaction. Children (4-16 years) with functional constipation and RFI participated. One week before disimpaction, a rectal examination was performed, symptoms of constipation were recorded, and the first CTT measurement was started. If RFI was determined, then patients were assigned randomly to receive enemas once daily or PEG (1.5 g/kg per day) for 6 consecutive days. During this period, the second CTT measurement was started and a child's behavior questionnaire was administered. Successful rectal disimpaction, defecation and fecal incontinence frequencies, occurrence of abdominal pain and watery stools, CTTs (before and after disimpaction), and behavior scores were assessed. Ninety-five patients were eligible, of whom 90 participated (male, n = 60; mean age: 7.5 +/- 2.8 years). Forty-six patients received enemas and 44 PEG, with 5 dropouts in each group. Successful disimpaction was achieved with enemas (80%) and PEG (68%; P = .28). Fecal incontinence and watery stools were reported more frequently with PEG (P...Continue Reading

References

Oct 1, 1989·The Journal of Clinical Investigation·H F HammerJ S Fordtran
Jan 1, 1987·Gastroenterology·A M MetcalfB G Wolff
Apr 1, 1988·Gastroenterology·L R SchillerJ S Fordtran
Nov 1, 1981·Diseases of the Colon and Rectum·P ArhanD Pellerin
Apr 1, 1995·European Journal of Pediatrics·M A BenningaJ A Taminiau
Apr 1, 1996·Diseases of the Colon and Rectum·J M GattusoC I Bartram
Oct 1, 1996·Journal of Pediatric Gastroenterology and Nutrition·M A BenningaJ A Taminiau
Nov 28, 1997·Child: Care, Health and Development·I Kristensson-Hallström, T Nilstun
Mar 5, 2002·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C E J Sloots, R J F Felt-Bersma
Sep 10, 2002·The Journal of Pediatrics·Nader N YoussefCarlo Di Lorenzo
Aug 2, 2003·Gastroenterology·Rijk van GinkelMarc A Benninga
Jul 23, 2004·Archives of Disease in Childhood·F de LorijnM A Benninga
Mar 1, 2005·Journal of Pediatric Gastroenterology and Nutrition·Marc BenningaAnnamaria Staiano
Jul 2, 2005·Journal of Pediatric Gastroenterology and Nutrition·Nader N YoussefJoel R Rosh
Nov 12, 2005·Pediatric Radiology·Fleur de LorijnMarc A Benninga
May 9, 2006·Gastroenterology·Andrée RasquinLynn S Walker
Sep 7, 2006·Journal of Pediatric Gastroenterology and Nutrition·UNKNOWN Constipation Guideline Committee of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
Sep 28, 2006·Jornal de pediatria·Francisca T V Faleiros, Nilton C Machado
Oct 13, 2006·The American Journal of Gastroenterology·Maartje M van den BergC Di Lorenzo
Aug 23, 2008·The British Journal of Surgery·S M P KochC G M I Baeten
Mar 4, 2009·Health and Quality of Life Outcomes·Marloes E J BongersMartha A Grootenhuis

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Citations

Jul 12, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Fleur P VeldersHenning Tiemeier
Mar 16, 2013·The American Journal of Clinical Hypnosis·Sara E Rosenquist
Dec 19, 2013·Journal of Pediatric Gastroenterology and Nutrition·M M TabbersM A Benninga
Sep 16, 2014·Journal of Pediatric Gastroenterology and Nutrition·Sherrie McNamara
Sep 16, 2014·Journal of Pediatric Gastroenterology and Nutrition·Merit M TabbersCarlo Di Lorenzo
Jun 11, 2010·Journal of Neurogastroenterology and Motility·Wei Zhao, Meiyun Ke
May 7, 2014·Journal of Pediatric Gastroenterology and Nutrition·Stephen B FreedmanSuzanne Schuh
Aug 3, 2011·Nature Reviews. Gastroenterology & Hepatology·Suzanne M MugieMarc A Benninga
Aug 15, 2013·Indian Journal of Pediatrics·Jaya Agarwal
Jun 28, 2011·European Journal of Pediatrics·Merit M TabbersMarc A Benninga
Sep 28, 2012·Journal of Pediatric Gastroenterology and Nutrition·Mariëtte Y M van der WulpHenkjan J Verkade
Apr 18, 2013·Journal of Pediatric Gastroenterology and Nutrition·Arik Alper, Dinesh S Pashankar
Dec 12, 2012·Expert Opinion on Pharmacotherapy·Daniël Robin Hoekman, Marc Alexander Benninga
Aug 2, 2011·Expert Opinion on Drug Safety·Herbert M van WeringMarc A Benninga
Mar 12, 2013·The Journal of Urology·Rosa BurgersMarc A Benninga
Oct 26, 2010·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Allison Beck Blackmer, Elizabeth Anne Farrington
Jul 24, 2013·Evidence-based Child Health : a Cochrane Review Journal·Morris GordonAdrian G Thomas
Aug 26, 2015·Revista chilena de pediatría·Alejandra Torres, Mónica González
Apr 16, 2015·Journal of Paediatrics and Child Health·Line ModinMarianne Jakobsen
Aug 12, 2015·Paediatric Drugs·Ilan J N KoppenMerit M Tabbers
Jul 22, 2015·Iranian Journal of Pediatrics·Majid NimrouziMohammad M Zarshenas
May 15, 2012·The Journal of Pediatrics·Rosa BurgersMarc A Benninga
Nov 21, 2012·The Journal of Pediatrics·Rosa BurgersMarc A Benninga
Feb 26, 2015·Journal of Pediatric Gastroenterology and Nutrition·Christine H Yang, Jaya Punati
Jul 28, 2016·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Mario C VieiraSolena Ziemer Kusma
Feb 10, 2016·Journal of Pediatric Gastroenterology and Nutrition·Ilan J N Koppen, Carlo Di Lorenzo
Dec 15, 2015·Journal of Pediatric Gastroenterology and Nutrition·Corrie E ChumpitaziBruno P Chumpitazi
Oct 11, 2013·Clinical Pediatrics·Uma Padhye Phatak, Dinesh S Pashankar
Jan 31, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·I J N KoppenM A Benninga
Aug 18, 2016·The Cochrane Database of Systematic Reviews·Morris GordonAdrian G Thomas
Oct 9, 2018·Journal of Paediatrics and Child Health·Misel TrajanovskaSharon Goldfeld
Jun 29, 2018·Journal of Pediatric Gastroenterology and Nutrition·Line ModinMarianne Skytte Jakobsen
Aug 25, 2020·Current Opinion in Pediatrics·Ricardo Medina-Centeno
Nov 2, 2013·JAAPA : Official Journal of the American Academy of Physician Assistants·Kristy L Luciano
May 10, 2016·Indian Pediatrics·Ujjal Poddar
Nov 23, 2016·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Miguel MínguezJavier Júdez
Feb 27, 2018·Paediatrics & Child Health·Alison NutterQuynh Doan
Dec 16, 2016·Journal of Pediatric Gastroenterology and Nutrition·Giovanni MosielloMarc A Benninga
Feb 20, 2018·World Journal of Clinical Pediatrics·Ariani WidodoYvan Vandenplas
Jul 18, 2016·Italian Journal of Pediatrics·Silvia SalvatoreUNKNOWN SIPPS Working Group on FGIDs

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