PMID: 11338072May 8, 2001Paper

Rectal inhibition by inferior rectal nerve stimulation in dogs: recognition of a new reflex--the 'voluntary anorectal inhibition reflex'

European Journal of Gastroenterology & Hepatology
A Shafik, Olfat El-Sibai

Abstract

The effect of inferior rectal nerve (IRN) stimulation on the rectum was studied, postulating that nerve stimulation might inhibit rectal contractility and could thus be used in the management of defecation disorders. The IRN was exposed through a para-anal incision in 12 dogs (18.2 +/- 3.3 SD kg, seven male, five female) and a cuff-type electrode was applied to the nerve. A balloon introduced into the rectum was filled with saline in increments of 5 ml. The rectal and rectal neck (anal canal) pressures, and the electromyographic (EMG) activity of the external anal sphincter (EAS) and Internal anal sphincter (IAS) were recorded until the balloon was expelled to the exterior. The test was repeated until the expulsion volume was reached, and the IRN was stimulated (pulse width 200 mu/s, charge density 2 to 6 microCi/cm2 per phase). The test was performed again following individual anaesthetization of the EAS and the IAS. At a mean rectal distending volume of 38.3 +/- 2.3 ml, the rectal pressure increased (P < 0.01), rectal neck pressure declined (P < 0.01), the EAS and IAS EMGs disappeared, and the balloon was expelled. IRN stimulation at a distending volume of 38.3 +/- 2.3 ml increased the EMG activity of the EAS, whereas the rec...Continue Reading

References

Jan 1, 1992·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·A ShafikB el-Said
May 1, 1989·The British Journal of Surgery·I T Khubchandani, J F Reed
Nov 1, 1986·The British Journal of Surgery·N L ChowcatP B Boulos
Jan 1, 1995·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·A ShafikE S Olfat
Jan 1, 1993·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·A Shafik
Apr 1, 1996·Diseases of the Colon and Rectum·J Garcia-AguilarR D Madoff

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Citations

Nov 25, 2006·International Urogynecology Journal and Pelvic Floor Dysfunction·Ahmed ShafikAli A Shafik
Aug 6, 2008·Techniques in Coloproctology·A P ZbarM Pescatori
Jul 11, 2006·Diseases of the Colon and Rectum·Yuqiang Nie, J D Z Chen
Aug 4, 2009·Best Practice & Research. Clinical Gastroenterology·Adeel Bajwa, Anton Emmanuel
Feb 18, 2005·Acta Obstetricia Et Gynecologica Scandinavica·Ahmed ShafikOlfat El-Sibai
Sep 13, 2006·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Ahmed ShafikAli A Shafik
Jul 29, 2006·World Journal of Gastroenterology : WJG·Ahmed ShafikAli A Shafik
Nov 1, 2007·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Ahmed ShafikOlfat El Sibai

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