Rectal misoprostol vs 15-methyl prostaglandin F2alpha for retained placenta after second-trimester delivery

American Journal of Obstetrics and Gynecology
Subha SundaramUsha Verma

Abstract

The purpose of this study was to compare rectal misoprostol (RM) with 15-methyl prostaglandin F2alpha (PGF(2alpha)) for the management of retained placenta after second-trimester deliveries. A retrospective study of all second-trimester deliveries between the years 2000 and 2005 was performed. Women were divided into 2 groups, depending on whether they received RM or PGF(2alpha) after the delivery. Three hundred three second-trimester deliveries were analyzed. The time from the administration of medications to the placental delivery was significantly shorter in women who received PGF(2alpha), compared with the RM group (49.5 vs 89 minutes; P < .01). Women who received PGF(2alpha) had lower rates of retained placenta (4.9% vs 12.4%; P = .02). The use of PGF(2alpha) after second-trimester deliveries results in shorter third stage of labor and lower rates of retained placenta compared with RM.

References

Aug 15, 2001·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Y T Li, C S Yin
Oct 18, 2002·Obstetrics and Gynecology·Jeanette LeaderKristine Richichi
Jul 11, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·N PrataM Potts

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Citations

Mar 12, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohammed S E ElsaftyAyman A Abou Elnoor
Jul 28, 2009·American Journal of Obstetrics and Gynecology·Jan E Dickinson, Dorota A Doherty
May 17, 2014·The Cochrane Database of Systematic Reviews·Carlos F Grillo-ArdilaNelcy Rodriguez-Malagon

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