Rectovaginal fistula after low anterior resection in Chinese patients with colorectal cancer

Oncotarget
Hongtu ZhengYe Xu

Abstract

Rectovaginal fistula is a postoperative complication of low anterior resection. We investigated the incidence of rectovaginal fistula (RVF) after low anterior resection, its risk factors and its optimal treatment. We analyzed data from 1,493 female patients who underwent low anterior resection for colorectal cancer between January 2006 and March 2016. We calculated the incidence of RVF and performed univariate and multivariate logistic regression analyses to identify risk factors. Twenty-four patients experienced RVF, giving an incidence of 1.61%. Univariate analysis revealed a short distance between the tumor and the anal verge (p < 0.001), longer surgery duration (p = 0.009), unsatisfactory anastomosis (p < 0.001), and greater intraoperative blood loss (p = 0.002) to be risk factors for RVF. Multivariate analysis showed that only distance between the tumor and the anal verge and unsatisfactory anastomosis were risk factors for RVF. Sixteen patients (66.7%) healed within a range of 30-1,225 days (median, 210 days). Twenty-one patients underwent surgery for diverting stoma; of those, 15 of them (71.4%) recovering after ostomy. These results indicate the primary risk factors for RVF are unsatisfactory anastomosis and short dista...Continue Reading

References

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Citations

May 26, 2020·Updates in Surgery·Giuliano BarugolaGiacomo Ruffo
Jan 28, 2019·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Limin Xia
Jan 6, 2021·International Journal of Surgery Case Reports·A A J GrüterJ B Tuynman
Jan 28, 2022·Female Pelvic Medicine & Reconstructive Surgery·Mufaddal K KaziAvanish P Saklani

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